Protein: FXYD6
FXYD domain-containing ion transport regulator 6 (Phosphohippolin)

Gene: FXYD6
Organism: Homo sapiens
Interactions: 113
UniProt ID: Q9H0Q3

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0017080 - sodium channel regulator activity
GO:0034220 - monoatomic ion transmembrane transport
GO:0042734 - presynaptic membrane
GO:0043269 - regulation of monoatomic ion transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

530966

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

2

High-throughput

0.691

High

871961

AT12A
Potassium-transporting ATPase alpha chain 2

1

2

High-throughput

0.691

High

1119742

S39AC
Zinc transporter ZIP12

2

2

High-throughput

0.628

High

1285264

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

3

3

High-throughput

0.616

High

183294

FFAR2
Free fatty acid receptor 2

2

3

High-throughput

0.606

High

238239

MOT2
Monocarboxylate transporter 2

2

2

High-throughput

0.606

High

315151

CLD7
Claudin-7

2

1

High-throughput

0.606

High

1037717

AQP6
Aquaporin-6

2

1

High-throughput

0.606

High

1060719

NTCP
Hepatic sodium/bile acid cotransporter

2

3

High-throughput

0.606

High

1108631

SOAT
Sodium-dependent organic anion transporter

2

3

High-throughput

0.606

High

1172932

LHPL2
LHFPL tetraspan subfamily member 2 protein

2

1

High-throughput

0.606

High

1216650

CLC10
C-type lectin domain family 10 member A

2

1

High-throughput

0.606

High

1251281

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

1

High-throughput

0.606

High

1285537

APH1A
Gamma-secretase subunit APH-1A

2

1

High-throughput

0.606

High

1310007

ZNT2
Proton-coupled zinc antiporter SLC30A2

2

1

High-throughput

0.606

High

1327979

S39A2
Zinc transporter ZIP2

2

2

High-throughput

0.606

High

1253887

SPP2B
Signal peptide peptidase-like 2B

2

0

High-throughput

0.602

High

1327992

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

3

2

High-throughput

0.597

High

274881

RHBL1
Rhomboid-related protein 1

2

0

High-throughput

0.580

High

380335

HG2A
HLA class II histocompatibility antigen gamma chain

2

0

High-throughput

0.580

High

626590

FPR2
N-formyl peptide receptor 2

2

0

High-throughput

0.580

High

816195

KCNJ6
G protein-activated inward rectifier potassium channel 2

2

0

High-throughput

0.580

High

816644

CXA8
Gap junction alpha-8 protein

2

0

High-throughput

0.580

High

1160109

RNK
Ribonuclease kappa

2

0

High-throughput

0.580

High

1233949

EMC5
ER membrane protein complex subunit 5

2

0

High-throughput

0.580

High

1241722

APCDL
Protein APCDD1-like

2

0

High-throughput

0.580

High

1291354

S47A1
Multidrug and toxin extrusion protein 1

2

0

High-throughput

0.580

High

1327988

RHCG
Ammonium transporter Rh type C

2

0

High-throughput

0.580

High

157653

MGST3
Glutathione S-transferase 3, mitochondrial

2

1

High-throughput

0.553

High

1068349

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

1

High-throughput

0.553

High

1192434

S35E3
Solute carrier family 35 member E3

2

1

High-throughput

0.553

High

1234016

SVOP
Synaptic vesicle 2-related protein

2

2

High-throughput

0.553

High

1235503

TM86B
Lysoplasmalogenase TMEM86B

2

1

High-throughput

0.553

High

1326293

ELOV4
Very long chain fatty acid elongase 4

2

1

High-throughput

0.553

High

1327980

S35C2
Solute carrier family 35 member C2

2

3

High-throughput

0.553

High

1327985

ELOV2
Very long chain fatty acid elongase 2

2

1

High-throughput

0.553

High

1129040

COL12
Collectin-12

1

1

High-throughput

0.536

High

1253535

CIP2A
Protein CIP2A

1

1

High-throughput

0.536

High

1327991

DYN3
Dynamin-3

1

1

High-throughput

0.536

High

372965

C4BPA
C4b-binding protein alpha chain

1

0

High-throughput

0.518

High

882553

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.518

High

182033

GPR42
G-protein coupled receptor 42

1

3

High-throughput

0.515

High

415486

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.513

High

941852

GPC5
Glypican-5 [Cleaved into: Secreted glypican-5]

1

0

High-throughput

0.513

High

1022351

TSN31
Tetraspanin-31

1

0

High-throughput

0.513

High

155636

TNPO2
Transportin-2

1

2

High-throughput

0.489

High

1038170

ATR
Serine/threonine-protein kinase ATR

1

1

High-throughput

0.489

High

1162205

BRAT1
BRCA1-associated ATM activator 1

1

1

High-throughput

0.489

High

1273393

GLMN
Glomulin

1

1

High-throughput

0.489

High

1327990

XPO7
Exportin-7

1

4

High-throughput

0.489

High

131326

CLD5
Claudin-5

1

1

High-throughput

0.481

High

243210

G37L1
G-protein coupled receptor 37-like 1

1

1

High-throughput

0.481

High

283336

BEST1
Bestrophin-1

1

1

High-throughput

0.481

High

1186301

MOT13
Monocarboxylate transporter 13

1

3

High-throughput

0.481

High

1203121

UN93A
Protein unc-93 homolog A

1

1

High-throughput

0.481

High

1255420

GP152
Probable G-protein coupled receptor 152

1

2

High-throughput

0.481

High

1262270

APH1B
Gamma-secretase subunit APH-1B

1

1

High-throughput

0.481

High

1327986

SCN3B
Sodium channel regulatory subunit beta-3

1

1

High-throughput

0.481

High

1327987

GPC5D
G-protein coupled receptor family C group 5 member D

1

1

High-throughput

0.481

High

216831

CREB3
Cyclic AMP-responsive element-binding protein 3

1

3

High-throughput

0.464

High

314454

NPT2B
Sodium-dependent phosphate transport protein 2B

1

0

High-throughput

0.460

High

672996

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

0

High-throughput

0.460

High

674078

V2R
Vasopressin V2 receptor

1

0

High-throughput

0.460

High

714717

TRFR
Thyrotropin-releasing hormone receptor

1

0

High-throughput

0.460

High

738036

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

0

Small-scale

0.460

High

1300356

MYCT
Proton myo-inositol cotransporter

1

0

High-throughput

0.460

High

1318442

S19A3
Thiamine transporter 2

1

0

High-throughput

0.460

High

1327989

LAT2
Large neutral amino acids transporter small subunit 2

1

0

High-throughput

0.460

High

497579

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.445

High

360396

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.439

High

1128711

F209A
Protein FAM209A

1

1

High-throughput

0.439

High

1327977

IF3M
Translation initiation factor IF-3, mitochondrial

1

1

High-throughput

0.439

High

49425

TMM72
Transmembrane protein 72

2

0

High-throughput

0.316

High

134633

PEX12
Peroxisome assembly protein 12

2

0

High-throughput

0.316

High

170946

PGRC2
Membrane-associated progesterone receptor component 2

2

0

High-throughput

0.316

High

1110084

AR13B
ADP-ribosylation factor-like protein 13B

2

0

High-throughput

0.316

High

1120698

NACHO
Novel acetylcholine receptor chaperone

2

0

High-throughput

0.316

High

1160605

TM154
Transmembrane protein 154

2

0

High-throughput

0.316

High

1170482

TMPPE
Transmembrane protein with metallophosphoesterase domain

2

0

High-throughput

0.316

High

1234926

JAGN1
Protein jagunal homolog 1

2

0

High-throughput

0.316

High

1262238

TM239
Transmembrane protein 239

2

0

High-throughput

0.316

High

1286639

T4S18
Transmembrane 4 L6 family member 18

2

0

High-throughput

0.316

High

1298165

TLCD4
TLC domain-containing protein 4

2

0

High-throughput

0.316

High

1300142

TM237
Transmembrane protein 237

2

0

High-throughput

0.316

High

1326095

DERL2
Derlin-2

2

0

High-throughput

0.316

High

1326894

MFF
Mitochondrial fission factor

2

0

High-throughput

0.316

High

1327978

CERS4
Ceramide synthase 4

2

0

High-throughput

0.316

High

1327984

OCAD1
OCIA domain-containing protein 1

2

0

High-throughput

0.316

High

233960

GDF9
Growth/differentiation factor 9

1

0

High-throughput

0.282

High

387483

P53
Cellular tumor antigen p53

1

0

High-throughput

0.282

High

537060

TRI27
Zinc finger protein RFP

1

0

High-throughput

0.282

High

980646

TLE1
Transducin-like enhancer protein 1

1

0

High-throughput

0.282

High

1034199

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.282

High

1130095

RBM48
RNA-binding protein 48

1

0

High-throughput

0.282

High

1295804

S35E1
Solute carrier family 35 member E1

1

0

High-throughput

0.282

High

1326587

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.282

High

1327983

HAUS2
HAUS augmin-like complex subunit 2

1

0

High-throughput

0.282

High

1263410

ATRIP
ATR-interacting protein

1

0

High-throughput

0.279

Low

1290223

SAAL1
Protein SAAL1

1

0

High-throughput

0.279

Low

309227

APOL3
Apolipoprotein L3

1

0

High-throughput

0.251

Low

1022059

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

1

0

High-throughput

0.251

Low

1128860

TMM31
Transmembrane protein 31

1

0

High-throughput

0.251

Low

1165139

TM205
Transmembrane protein 205

1

0

High-throughput

0.251

Low

1293880

TM41A
Transmembrane protein 41A

1

0

High-throughput

0.251

Low

1295772

RN170
E3 ubiquitin-protein ligase RNF170

1

0

High-throughput

0.251

Low

1296512

F210B
Protein FAM210B, mitochondrial

1

0

High-throughput

0.251

Low

1327981

KISHB
Protein kish-B

1

0

High-throughput

0.251

Low

1327982

TM14B
Transmembrane protein 14B

1

0

High-throughput

0.251

Low

1327993

TMX2
Thioredoxin-related transmembrane protein 2

1

0

High-throughput

0.251

Low

1327994

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.251

Low

1172808

Q6ZUH1
cDNA FLJ43719 fis, clone TESOP2006060

1

0

High-throughput

0.238

Low

1294323

Q96I30
GPR108 protein

1

0

High-throughput

0.238

Low

1137073

PRAM5
PRAME family member 5

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024