HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: UBN2 (Q6ZU65)
Ubinuclein-2
Gene: UBN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	33961781, 36089195
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	HUN~Histone
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 1347
+	Hs
		934910 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		UBN2_HUMAN (1-1347): 0: 768: 100.00
+	Hs
		828277 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		UBN2_HUMAN (1-1347): 0: 768: 100.00
+	Hs
		934872 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		ARID2_HUMAN (663-1291): 2.26e-28: 126: 14.03
+	Hs
		952399 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		ARID2_HUMAN (663-1291): 2.26e-28: 126: 14.03
+	Hs
		935004 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		KMT2C_HUMAN (855-1346): 4.26e-15: 83.3: 12.31
+	Hs
		952479 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		KMT2C_HUMAN (855-1346): 4.26e-15: 83.3: 12.31
+	Hs
		1086228 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		KMT2C_HUMAN (855-1346): 4.26e-15: 83.3: 12.31
+	Hs
		1174600 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		KMT2C_HUMAN (855-1346): 4.26e-15: 83.3: 12.31
+	Hs
		935265 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		UBN1_HUMAN (773-1345): 3.71e-12: 73.2: 14.95
+	Hs
		952642 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		UBN1_HUMAN (773-1345): 3.71e-12: 73.2: 14.95
+	Hs
		934908 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		SRCAP_HUMAN (578-1060): 1.27e-11: 72.1: 9.92
+	Hs
		952426 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		SRCAP_HUMAN (578-1060): 1.27e-11: 72.1: 9.92
+	Mm
		101827 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		F8WI37_MOUSE (955-1346): 3.06e-10: 67.5: 9.18
+	Hs
		934763 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		MDC1_HUMAN (741-1257): 8.44e-09: 62.7: 14.66
+	Hs
		952338 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		MDC1_HUMAN (741-1257): 8.44e-09: 62.7: 14.66
+	Sc
		730797 CENPA_YEAST (18-134): 3.39e-40: 135: 56.67		SEC31_YEAST (623-983): 2.39e-09: 64.4: 8.59