HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: TF7L2 (Q9NQB0)
Transcription factor 7-like 2 (HMG box transcription factor 4) (T-cell-specific transcription factor 4) (T-cell factor 4) (TCF-4) (hTCF-4)
Gene: TCF7L2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36089195
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 619
+	Hs
		727961 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		SOX11_HUMAN (344-464): 5.08e-36: 142: 26.40
+	Hs
		935143 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		CIC_HUMAN (43-578): 1.85e-33: 139: 15.01
+	Hs
		952567 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		CIC_HUMAN (43-578): 1.85e-33: 139: 15.01
+	Hs
		727874 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		SOX6_HUMAN (85-501): 1.65e-33: 138: 11.66
+	Hs
		331780 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		NSD2_HUMAN (251-564): 1.22e-30: 130: 13.97
+	Hs
		1157221 H3C_HUMAN (1-136): 1.99e-56: 173: 95.59		CIC_HUMAN (43-578): 1.85e-33: 139: 15.01
+	Hs
		331787 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		NSD2_HUMAN (251-564): 1.22e-30: 130: 13.97
+	Hs
		331823 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		NSD2_HUMAN (251-564): 1.22e-30: 130: 13.97
+	Hs
		331833 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		NSD2_HUMAN (251-564): 1.22e-30: 130: 13.97
+	Mm
		952739 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		SSRP1_MOUSE (333-509): 6.21e-29: 124: 17.98
+	Hs
		934695 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89
+	Hs
		935263 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		HM20A_HUMAN (250-461): 2.79e-27: 115: 14.15
+	Hs
		952293 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89
+	Hs
		952640 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		HM20A_HUMAN (250-461): 2.79e-27: 115: 14.15
+	Hs
		996726 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89
+	Hs
		331748 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		NSD2_HUMAN (251-564): 1.22e-30: 130: 13.97
+	Hs
		828208 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89
+	Hs
		828385 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		HM20A_HUMAN (250-461): 2.79e-27: 115: 14.15
+	Hs
		175769 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		HMGB3_HUMAN (354-438): 3.21e-09: 59.2: 17.24
+	Hs
		175771 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		HMGB3_HUMAN (354-438): 3.21e-09: 59.2: 17.24