HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: TYB10 (P63313)
Thymosin beta-10
Gene: TMSB10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	35271311, 38334954
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Thymosin
Common GO terms	GO:0005737 - cytoplasm GO:0005856 - cytoskeleton
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 44
+	Hs
		993896 ACTBL_HUMAN (2-375): 0: 735: 91.71		TYB10_HUMAN (1-44): 1.34e-10: 51.4: 100.00
+	Hs
		974939 ACTBL_HUMAN (2-375): 0: 735: 91.71		TYB4_HUMAN (1-41): 1.33e-09: 48.7: 78.05
+	Hs
		993125 ACTG_HUMAN (1-375): 0: 601: 98.93		TYB10_HUMAN (1-44): 1.34e-10: 51.4: 100.00
+	Hs
		952715 ACTB_HUMAN (1-375): 0: 603: 100.00		TYB4_HUMAN (1-41): 1.33e-09: 48.7: 78.05
+	Hs
		974918 ACTG_HUMAN (1-375): 0: 601: 98.93		TYB4_HUMAN (1-41): 1.33e-09: 48.7: 78.05
+	Hs
		993883 ACTS_HUMAN (2-375): 0: 592: 93.58		TYB10_HUMAN (1-44): 1.34e-10: 51.4: 100.00
+	Hs
		977669 ACTA_HUMAN (2-375): 0: 591: 94.12		TYB10_HUMAN (1-44): 1.34e-10: 51.4: 100.00
+	Hs
		974921 ACTC_HUMAN (2-375): 0: 592: 94.12		TYB4_HUMAN (1-41): 1.33e-09: 48.7: 78.05
+	Hs
		974923 ACTS_HUMAN (2-375): 0: 592: 93.58		TYB4_HUMAN (1-41): 1.33e-09: 48.7: 78.05
+	Hs
		974919 ACTH_HUMAN (2-375): 0: 589: 93.58		TYB4_HUMAN (1-41): 1.33e-09: 48.7: 78.05