HitPredict

Interactor 1: H33 (P84244)
Histone H3.3
Gene: H3-3a

Interactor 2: Q6AXH7 (Q6AXH7)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356)
Gene: Ezh2

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	23624931
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	Histone~preSET_CXC, Histone~SET
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Mm			1 742
+	Mm
		952747 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		EZH2_MOUSE (1-742): 0: 918: 98.00
+	Hs
		934804 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		EZH2_HUMAN (1-742): 0: 910: 96.41
+	Hs
		935251 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		EHMT1_HUMAN (430-728): 5.9e-72: 257: 23.51
+	Hs
		935204 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		SETD2_HUMAN (350-728): 2.41e-71: 256: 19.54
+	Hs
		934681 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		KMT2A_HUMAN (243-729): 1.42e-70: 254: 18.13
+	Hs
		935237 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		SUV92_HUMAN (424-730): 1.9e-76: 254: 23.78
+	Hs
		203659 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		SUV91_HUMAN (417-727): 3.33e-76: 253: 22.63
+	Hs
		203664 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		SUV91_HUMAN (417-727): 3.33e-76: 253: 22.63
+	Hs
		935126 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		EHMT2_HUMAN (430-728): 1.13e-66: 241: 24.14
+	Mm
		952777 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		EHMT2_MOUSE (430-728): 7.68e-67: 242: 24.45
+	Hs
		935276 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		ASH1L_HUMAN (543-728): 3.01e-56: 211: 30.85
+	Hs
		331780 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		NSD2_HUMAN (551-723): 2.46e-55: 208: 30.56
+	Hs
		331787 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		NSD2_HUMAN (551-723): 2.46e-55: 208: 30.56
+	Hs
		935205 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		NSD3_HUMAN (551-723): 1.64e-54: 205: 30.56
+	Hs
		935129 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		NSD1_HUMAN (550-725): 1.73e-53: 203: 29.51
+	Hs
		935374 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		SET1B_HUMAN (615-728): 1.13e-18: 93.6: 40.52
+	Mm
		952758 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		SET1B_MOUSE (615-728): 8.12e-19: 94: 40.52
+	Hs
		165661 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		SET1A_HUMAN (607-728): 2.37e-18: 92.4: 38.71
+	Mm
		93307 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		SET1A_MOUSE (607-728): 1.95e-18: 92.8: 38.71
+	Hs
		935368 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		KMT2B_HUMAN (602-729): 2.48e-17: 89.4: 39.54