HitPredict

Interactor 1: H33 (P84244)
Histone H3.3
Gene: H3-3a

Interactor 2: EHMT2 (Q9Z148)
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Protein G9a)
Gene: EHMT2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	15939934
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Histone~SET
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0007286 - spermatid development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Mm			1 1263
+	Hs
		935126 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		EHMT2_HUMAN (78-1263): 0: 867: 94.97
+	Hs
		952553 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		EHMT2_HUMAN (78-1263): 0: 867: 94.97
+	Hs
		1086279 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		EHMT2_HUMAN (78-1263): 0: 867: 94.97
+	Hs
		1174632 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		EHMT2_HUMAN (78-1263): 0: 867: 94.97
+	Hs
		935251 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		EHMT1_HUMAN (80-1259): 0: 656: 47.87
+	Hs
		952633 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		EHMT1_HUMAN (80-1259): 0: 656: 47.87
+	Hs
		1086320 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		EHMT1_HUMAN (80-1259): 0: 656: 47.87
+	Dm
		115784 H3_DROME (1-136): 5.32e-59: 180: 97.06		M9PGH7_DROME (55-1263): 4.07e-147: 487: 23.30
+	Hs
		203659 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		SUV91_HUMAN (914-1230): 8.33e-88: 293: 31.53
+	Hs
		203664 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		SUV91_HUMAN (914-1230): 8.33e-88: 293: 31.53
+	Hs
		203722 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		SUV91_HUMAN (914-1230): 8.33e-88: 293: 31.53
+	At
		886462 H33_ARATH (1-136): 3.83e-60: 183: 95.59		SUVH4_ARATH (964-1230): 7.89e-84: 288: 29.13
+	Hs
		935237 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		SUV92_HUMAN (988-1230): 4.56e-86: 288: 36.50
+	Hs
		952627 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		SUV92_HUMAN (988-1230): 4.56e-86: 288: 36.50
+	Hs
		934710 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		ANK3_HUMAN (674-1137): 2.34e-64: 243: 17.67
+	Sp
		223811 H31_SCHPO (1-136): 1.12e-57: 177: 91.91		CLR4_SCHPO (977-1229): 2.64e-36: 146: 34.95
+	Dm
		356073 H3_DROME (1-136): 5.32e-59: 180: 97.06		SUV39_DROME (987-1229): 8e-29: 125: 37.22
+	At
		886666 H31_ARATH (1-136): 1.05e-58: 179: 94.85		SUVR2_ARATH (978-1229): 2.89e-28: 124: 30.65
+	Hs
		934668 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		ANK2_HUMAN (2-661): 3.66e-14: 80.2: 11.97
+	Hs
		965127 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		ANK2_HUMAN (2-661): 3.66e-14: 80.2: 11.97