HitPredict

Interactor 1: PR20A (P86496)
Proline-rich protein 20A
Gene: PRR20A

Interactor 2: SIAH1 (Q8IUQ4)
E3 ubiquitin-protein ligase SIAH1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH1) (Seven in absentia homolog 1) (Siah-1) (Siah-1a)
Gene: SIAH1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.50	0.618

Property	Details
Experiments	25416956, 32296183, 28514442, 33961781
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 221 Hs			1 282
+	Hs
		952974 PR20E_HUMAN (1-221): 8.6e-119: 338: 100.00		SIAH1_HUMAN (1-282): 7.29e-121: 348: 100.00
+	Hs
		952992 PR20C_HUMAN (1-221): 8.6e-119: 338: 100.00		SIAH1_HUMAN (1-282): 7.29e-121: 348: 100.00
+	Hs
		953026 PR20D_HUMAN (1-221): 8.6e-119: 338: 100.00		SIAH1_HUMAN (1-282): 7.29e-121: 348: 100.00
+	Hs
		199107 PR20E_HUMAN (1-221): 8.6e-119: 338: 100.00		SIAH2_HUMAN (28-282): 1.74e-103: 306: 83.20
+	Hs
		199108 PR20A_HUMAN (1-221): 8.6e-119: 338: 100.00		SIAH2_HUMAN (28-282): 1.74e-103: 306: 83.20