HitPredict

Interactor 1: CWC2 (P87126)
Pre-mRNA-splicing factor cwf2 (Complexed with cdc5 protein 2) (Pre-mRNA-processing protein 3)
Gene: cwf2

Interactor 2: RU2A (Q9USX8)
U2 small nuclear ribonucleoprotein A' (U2 snRNP A')
Gene: lea1

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.72	1.00	0.849

Property	Details
Experiments	26771498, 21386897, 24442611
Identification Methods	two hybrid, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	LRR_9~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0071014 - post-mRNA release spliceosomal complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 388 Sp			1 239
+	Hs
		453920 RBM22_HUMAN (84-275): 9.1e-72: 232: 22.82		RU2A_HUMAN (1-238): 5.86e-40: 139: 41.60
+	Sc
		997042 CWC2_YEAST (46-295): 4.28e-58: 194: 36.86		RU2A_YEAST (1-235): 1.06e-45: 154: 24.70
+	Sp
		678720 PABP_SCHPO (55-387): 8.33e-46: 168: 10.17		RU2A_SCHPO (1-239): 3.18e-43: 147: 100.00
+	Sc
		960477 NAM8_YEAST (33-248): 7.51e-24: 104: 12.22		RU2A_YEAST (1-235): 1.06e-45: 154: 24.70
+	Sc
		376961 PABP_YEAST (2-172): 1.37e-15: 80.2: 11.05		RU2A_YEAST (1-235): 1.06e-45: 154: 24.70
+	At
		1351891 RB45B_ARATH (149-378): 1.1e-14: 76.7: 10.61		BRL2_ARATH (1-198): 5.21e-16: 78.7: 11.61