Interactor 1: TRXR1 (P91938)
Thioredoxin reductase 1, mitochondrial (EC 1.8.1.9)
Gene: TRXR1

Interactor 2: TRXR2 (Q9VNT5)
Thioredoxin reductase 2, mitochondrial (EC 1.8.1.9)
Gene: TRXR2

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 22036573
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pyr_redox_2~Pyr_redox_2, Pyr_redox_2~Pyr_redox_dim, Pyr_redox_dim~Pyr_redox_dim
Common GO terms GO:0004791 - thioredoxin-disulfide reductase (NADPH) activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006749 - glutathione metabolic process
and 3 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 596
Dm

1 516
+ Dm
+ Hs
+ Hs
+ Rn
+ At
+ Sp
+ Ec
+ Sc
+ Ec
+ Sc
+ Mp

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Last updated: 15 Jul 2024