HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: SUN2 (Q9UH99)
SUN domain-containing protein 2 (Protein unc-84 homolog B) (Rab5-interacting protein) (Rab5IP) (Sad1/unc-84 protein-like 2)
Gene: SUN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007097 - nuclear migration GO:0030335 - positive regulation of cell migration
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 717
+	Hs
		1433562 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		SUN2_HUMAN (1-717): 0: 848: 100.00
+	Hs
		988799 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		SUN2_HUMAN (1-717): 0: 848: 100.00
+	Hs
		1015883 RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73		SUN2_HUMAN (1-717): 0: 848: 100.00
+	Hs
		962604 RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48		SUN2_HUMAN (1-717): 0: 848: 100.00
+	Hs
		581359 RAC2_HUMAN (1-191): 1.01e-77: 232: 68.75		SUN2_HUMAN (1-717): 0: 848: 100.00
+	Hs
		466512 RHOC_HUMAN (5-191): 3.38e-76: 228: 52.41		SUN2_HUMAN (1-717): 0: 848: 100.00
+	Hs
		953741 RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32		SUN2_HUMAN (1-717): 0: 848: 100.00
+	Hs
		321042 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		SUN1_HUMAN (1-715): 0: 780: 33.51
+	Hs
		320966 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		SUN1_HUMAN (1-715): 0: 780: 33.51
+	Hs
		320961 CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00		SUN1_HUMAN (1-715): 0: 780: 33.51
+	Hs
		320968 RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73		SUN1_HUMAN (1-715): 0: 780: 33.51
+	Hs
		320963 RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48		SUN1_HUMAN (1-715): 0: 780: 33.51
+	Hs
		320939 RAC2_HUMAN (1-191): 1.01e-77: 232: 68.75		SUN1_HUMAN (1-715): 0: 780: 33.51
+	Hs
		320932 RHOC_HUMAN (5-191): 3.38e-76: 228: 52.41		SUN1_HUMAN (1-715): 0: 780: 33.51
+	Hs
		320960 RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32		SUN1_HUMAN (1-715): 0: 780: 33.51