HitPredict

Interactor 1: PP4C (P97470)
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) (Protein phosphatase X) (PP-X)
Gene: Ppp4c

Interactor 2: TBK1 (Q9WUN2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26363053
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 307 Mm			1 729
+	Hs
		890962 PP4C_HUMAN (1-307): 0: 536: 100.00		IKKE_HUMAN (1-715): 7.37e-150: 455: 48.54
+	Hs
		915188 PP2AB_HUMAN (6-307): 0: 523: 65.23		IKKE_HUMAN (1-715): 7.37e-150: 455: 48.54
+	Hs
		158435 PP4C_HUMAN (1-307): 0: 536: 100.00		IKKB_HUMAN (9-709): 4.06e-128: 400: 18.63
+	Hs
		158442 PP2AA_HUMAN (6-307): 0: 522: 65.89		IKKB_HUMAN (9-709): 4.06e-128: 400: 18.63
+	Hs
		158438 PP1A_HUMAN (2-304): 0: 517: 43.89		IKKB_HUMAN (9-709): 4.06e-128: 400: 18.63
+	Mm
		291448 PP1A_MOUSE (2-304): 0: 518: 44.20		IKKB_MOUSE (9-709): 3.3e-126: 395: 18.90
+	Hs
		167506 PP4C_HUMAN (1-307): 0: 536: 100.00		IKKA_HUMAN (9-643): 5.48e-119: 375: 20.53
+	Hs
		167511 PP2AB_HUMAN (6-307): 0: 523: 65.23		IKKA_HUMAN (9-643): 5.48e-119: 375: 20.53
+	Hs
		167515 PP2AA_HUMAN (6-307): 0: 522: 65.89		IKKA_HUMAN (9-643): 5.48e-119: 375: 20.53
+	Hs
		931058 PP2AA_HUMAN (6-307): 0: 522: 65.89		MRCKB_HUMAN (6-715): 1.84e-111: 372: 17.21
+	Hs
		167510 PP1A_HUMAN (2-304): 0: 517: 43.89		IKKA_HUMAN (9-643): 5.48e-119: 375: 20.53
+	Hs
		625340 PP2AA_HUMAN (6-307): 0: 522: 65.89		CDK2_HUMAN (6-312): 9.48e-120: 362: 20.97
+	Hs
		625180 PP1G_HUMAN (1-304): 0: 518: 43.81		CDK2_HUMAN (6-312): 9.48e-120: 362: 20.97
+	Hs
		915261 PP2AB_HUMAN (6-307): 0: 523: 65.23		MARK4_HUMAN (9-311): 1.6e-86: 290: 25.16
+	Hs
		647866 PP2AB_HUMAN (6-307): 0: 523: 65.23		MARK3_HUMAN (9-265): 1.07e-85: 288: 27.91
+	Hs
		738092 PP1G_HUMAN (1-304): 0: 518: 43.81		MARK1_HUMAN (9-407): 3.57e-86: 290: 24.57
+	Hs
		930841 PP2AA_HUMAN (6-307): 0: 522: 65.89		KCC1A_HUMAN (7-297): 8.74e-87: 279: 24.40
+	Hs
		262251 PP1A_HUMAN (2-304): 0: 517: 43.89		ULK1_HUMAN (13-222): 3.4e-26: 117: 34.10
+	Ce
		108336 PP2A_CAEEL (2-307): 0: 523: 63.73		UNC51_CAEEL (13-221): 2.45e-21: 101: 31.96
+	Hs
		883143 PP2AA_HUMAN (6-307): 0: 522: 65.89		HUNK_HUMAN (15-224): 2.85e-21: 100: 33.95