Protein: PRAF2
PRA1 family protein 2

Gene: PRAF2
Organism: Homo sapiens
Interactions: 115
UniProt ID: O60831

Gene Ontology (top 5):
GO:0010008 - endosome membrane
GO:0015031 - protein transport
GO:0015813 - L-glutamate transmembrane transport
GO:0016020 - membrane
GO:0098793 - presynapse

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

257623

DLK1
Protein delta homolog 1

4

1

High-throughput

0.691

High

257590

PRAF3
PRA1 family protein 3

3

5

Small-scale

0.650

High

257604

HMOX2
Heme oxygenase 2

3

0

High-throughput

0.638

High

257678

RTN4
Reticulon-4

2

10

High-throughput

0.611

High

257624

REEP5
Receptor expression-enhancing protein 5

3

8

High-throughput

0.609

High

257639

AGRD1
Adhesion G-protein coupled receptor D1

2

1

High-throughput

0.606

High

257588

XRP2
Protein XRP2

2

0

High-throughput

0.585

High

257593

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

1

High-throughput

0.584

High

257591

ABHGA
Phosphatidylserine lipase ABHD16A

2

0

High-throughput

0.580

High

257662

TLCD4
TLC domain-containing protein 4

2

0

High-throughput

0.580

High

257663

ZDH15
Palmitoyltransferase ZDHHC15

2

0

High-throughput

0.580

High

257649

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

2

0

High-throughput

0.576

High

257618

TSN5
Tetraspanin-5

2

5

High-throughput

0.558

High

257625

IFM3
Interferon-induced transmembrane protein 3

2

2

High-throughput

0.558

High

257659

TSN17
Tetraspanin-17

2

5

High-throughput

0.558

High

257609

CXA5
Gap junction alpha-5 protein

2

3

High-throughput

0.553

High

257611

CXA8
Gap junction alpha-8 protein

2

3

High-throughput

0.553

High

257629

AQP6
Aquaporin-6

2

1

High-throughput

0.553

High

257635

SOAT
Sodium-dependent organic anion transporter

2

1

High-throughput

0.553

High

257643

RETR3
Reticulophagy regulator 3

2

3

High-throughput

0.553

High

257644

CLC10
C-type lectin domain family 10 member A

2

1

High-throughput

0.553

High

257650

DHB11
Estradiol 17-beta-dehydrogenase 11

2

2

High-throughput

0.553

High

257653

GP152
Probable G-protein coupled receptor 152

2

7

High-throughput

0.553

High

257666

RNF5
E3 ubiquitin-protein ligase RNF5

2

2

High-throughput

0.553

High

257674

CIA2A
Cytosolic iron-sulfur assembly component 2A

2

2

High-throughput

0.553

High

257675

REEP4
Receptor expression-enhancing protein 4

2

8

High-throughput

0.553

High

257679

MID51
Mitochondrial dynamics protein MIEF1

2

2

High-throughput

0.553

High

257681

TM14B
Transmembrane protein 14B

2

1

High-throughput

0.553

High

257685

NDRG4
Protein NDRG4

2

4

High-throughput

0.553

High

257687

TMX2
Thioredoxin-related transmembrane protein 2

2

2

High-throughput

0.553

High

257598

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.543

High

167149

T4S5
Transmembrane 4 L6 family member 5

1

1

High-throughput

0.536

High

257605

CTR1
High affinity cationic amino acid transporter 1

1

2

High-throughput

0.536

High

257657

YIPF5
Protein YIPF5

1

1

High-throughput

0.536

High

208931

CYB5B
Cytochrome b5 type B

1

0

High-throughput

0.513

High

257628

VAC14
Protein VAC14 homolog

1

0

High-throughput

0.513

High

257636

VPS53
Vacuolar protein sorting-associated protein 53 homolog

1

0

High-throughput

0.513

High

164883

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

2

High-throughput

0.489

High

257621

RAB1A
Ras-related protein Rab-1A

1

6

High-throughput

0.489

High

257670

TX101
Testis-expressed protein 101

1

2

High-throughput

0.489

High

257671

TSN10
Tetraspanin-10

1

4

High-throughput

0.489

High

48455

ESYT2
Extended synaptotagmin-2

1

3

High-throughput

0.479

High

173788

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

5

High-throughput

0.479

High

257586

PRAF2
PRA1 family protein 2

1

5

Small-scale

0.479

High

257592

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.479

High

257597

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.479

High

257601

LMNB1
Lamin-B1

1

5

High-throughput

0.479

High

257614

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.479

High

257617

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.479

High

257619

ARF6
ADP-ribosylation factor 6

1

7

High-throughput

0.479

High

257627

CKAP4
Cytoskeleton-associated protein 4

1

1

High-throughput

0.479

High

257655

LPAR1
Lysophosphatidic acid receptor 1

1

5

High-throughput

0.479

High

257658

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.479

High

257665

SEC62
Translocation protein SEC62

1

1

High-throughput

0.479

High

257668

ESYT1
Extended synaptotagmin-1

1

3

High-throughput

0.479

High

257669

DERL1
Derlin-1

1

2

High-throughput

0.479

High

257682

ELOV5
Very long chain fatty acid elongase 5

1

2

High-throughput

0.479

High

257683

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

49275

SHOT1
Shootin-1

1

1

High-throughput

0.470

High

257616

CCR5
C-C chemokine receptor type 5

1

4

Small-scale

0.470

High

257595

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

257610

COIL
Coilin

1

0

High-throughput

0.458

High

257612

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

257615

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

257626

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

257620

RHOB
Rho-related GTP-binding protein RhoB

1

8

Small-scale

0.457

High

257664

SL9A7
Sodium/hydrogen exchanger 7

1

1

High-throughput

0.445

High

163211

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

2

High-throughput

0.437

High

217595

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

257599

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

257602

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

257603

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.437

High

257607

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

257613

RAB5C
Ras-related protein Rab-5C

1

11

High-throughput

0.437

High

257622

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

257638

TECT3
Tectonic-3

1

3

High-throughput

0.437

High

257641

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

257648

CXD3
Gap junction delta-3 protein

1

3

High-throughput

0.437

High

257656

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

257660

TECT2
Tectonic-2

1

3

High-throughput

0.437

High

257667

DUS9
Dual specificity protein phosphatase 9

1

2

High-throughput

0.437

High

257672

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

1

High-throughput

0.437

High

257673

DUS21
Dual specificity protein phosphatase 21

1

2

High-throughput

0.437

High

257680

DUS22
Dual specificity protein phosphatase 22

1

3

High-throughput

0.437

High

257686

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.437

High

191948

TEX28
Testis-specific protein TEX28

1

0

High-throughput

0.426

High

257654

SSMM1
Serine-rich single-pass membrane protein 1

1

0

High-throughput

0.426

High

257677

ANKH
Mineralization regulator ANKH

1

0

High-throughput

0.426

High

257594

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.407

High

257634

S35G1
Solute carrier family 35 member G1

1

1

High-throughput

0.407

High

257645

S22A9
Organic anion transporter 7

1

1

High-throughput

0.407

High

257651

MINY2
Ubiquitin carboxyl-terminal hydrolase MINDY-2

3

0

High-throughput

0.347

High

139778

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

2

0

High-throughput

0.316

High

257596

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.316

High

257606

3HIDH
3-hydroxyisobutyrate dehydrogenase, mitochondrial

2

0

High-throughput

0.316

High

257647

MCEM1
Mast cell-expressed membrane protein 1

2

0

High-throughput

0.316

High

257652

AGR3
Anterior gradient protein 3

2

0

High-throughput

0.316

High

257587

SG2A1
Mammaglobin-B

1

0

High-throughput

0.279

Low

257600

DPEP1
Dipeptidase 1

1

0

High-throughput

0.279

Low

257608

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.279

Low

257630

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.279

Low

257637

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.279

Low

257642

MCM10
Protein MCM10 homolog

1

0

High-throughput

0.279

Low

257646

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

257676

PACC1
Proton-activated chloride channel

1

0

High-throughput

0.279

Low

133715

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.249

Low

190753

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.249

Low

257589

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

257632

E2F4
Transcription factor E2F4

1

0

High-throughput

0.249

Low

257633

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.249

Low

257640

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

257661

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

257684

AAKG3
5'-AMP-activated protein kinase subunit gamma-3

1

0

High-throughput

0.249

Low

257631

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025