Interactor 1: SMAD4 (P97471)
Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4 homolog) (SMAD family member 4) (SMAD 4) (Smad4)
Gene: SMAD4

Interactor 2: GATA4 (Q08369)
Transcription factor GATA-4 (GATA-binding factor 4)
Gene: GATA4

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.573

The method score is based on:

Property Details
Experiments 14662776
Identification Methods pull down, affinity chromatography technology, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
and 21 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 551
Mm

1 441
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ Hs
+ Dm
+ Ce

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Last updated: 15 Jul 2024