Interactor 1: SHPS1 (P97710)
Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (Macrophage membrane protein MFP150) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (CD antigen CD172a)
Gene: Sirpa

Interactor 2: NPHN (Q9R044)
Nephrin (Renal glomerulus-specific cell adhesion receptor)
Gene: Nphs1

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 22747997
Identification Methods anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~fn3, C1-set~Ig_3, C2-set_2~V-set, V-set~fn3, I-set~V-set, Ig_3~V-set
Common GO terms GO:0005886 - plasma membrane
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 509
Rn

1 1252
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs
+ Ce
+ Hs
+ Rn
+ Hs
+ Dm
+ Dr
+ Dm
+ Mm
+ Hs
+ Dm

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Last updated: 15 Jul 2024