HitPredict

Interactor 1: DAB2 (P98078)
Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Mitogen-responsive phosphoprotein)
Gene: DAB2

Interactor 2: DVL3 (Q61062)
Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3)
Gene: DVL3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	12805222
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~PID
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 766 Mm			1 716
+	Hs
		957206 DAB2_HUMAN (1-766): 8.87e-80: 273: 81.76		DVL3_HUMAN (1-716): 9.11e-161: 482: 99.02
+	Mm
		957140 DAB2_MOUSE (1-766): 9.01e-96: 316: 100.00		DVL2_MOUSE (3-716): 4.25e-125: 391: 63.77
+	Hs
		150694 DAB2_HUMAN (1-766): 8.87e-80: 273: 81.76		DVL1_HUMAN (1-716): 1.16e-141: 433: 62.83
+	Hs
		150949 DAB2_HUMAN (1-766): 8.87e-80: 273: 81.76		DVL2_HUMAN (3-716): 1.72e-120: 379: 65.03
+	Hs
		151237 GULP1_HUMAN (23-287): 5.01e-59: 204: 21.35		DVL2_HUMAN (3-716): 1.72e-120: 379: 65.03
+	Hs
		150911 NUMB_HUMAN (26-678): 6e-47: 179: 14.24		DVL2_HUMAN (3-716): 1.72e-120: 379: 65.03
+	Mm
		957153 DAB2_MOUSE (1-766): 9.01e-96: 316: 100.00		PARD3_MOUSE (119-419): 3.04e-15: 82.3: 16.01
+	Mm
		1143409 Q8BZM2_MOUSE (2-228): 5.5e-45: 170: 18.18		DLG4_MOUSE (81-627): 5.07e-49: 185: 13.50
+	Mm
		1143393 ANS1B_MOUSE (2-231): 5.14e-41: 164: 17.95		DLG4_MOUSE (81-627): 5.07e-49: 185: 13.50
+	Hs
		833631 NUMB_HUMAN (26-678): 6e-47: 179: 14.24		PARD3_HUMAN (44-645): 3.07e-43: 170: 14.22
+	Mm
		887083 ANS1A_MOUSE (1-248): 1.21e-38: 156: 19.05		DLG4_MOUSE (81-627): 5.07e-49: 185: 13.50
+	Mm
		1143442 DP13A_MOUSE (20-249): 2.95e-38: 154: 14.17		DLG4_MOUSE (81-627): 5.07e-49: 185: 13.50
+	Hs
		942395 DP13A_HUMAN (20-242): 4.12e-37: 150: 12.45		DLG4_HUMAN (81-627): 2.86e-48: 183: 13.14
+	Hs
		833625 NUMB_HUMAN (26-678): 6e-47: 179: 14.24		LNX2_HUMAN (5-331): 1e-21: 102: 12.43
+	Hs
		833629 NUMB_HUMAN (26-678): 6e-47: 179: 14.24		LNX1_HUMAN (2-331): 9.08e-20: 96.1: 14.75
+	Mm
		1265184 NUMB_MOUSE (26-678): 7.52e-45: 173: 13.19		LNX2_MOUSE (5-331): 1.76e-20: 98.4: 12.75
+	Mm
		250665 NUMB_MOUSE (26-678): 7.52e-45: 173: 13.19		LNX1_MOUSE (8-330): 3.19e-18: 91.1: 14.86
+	Hs
		1252371 ANS1A_HUMAN (1-248): 2.57e-37: 152: 19.44		LNX1_HUMAN (2-331): 9.08e-20: 96.1: 14.75
+	Hs
		269170 DAB1_HUMAN (11-617): 1.62e-37: 150: 23.57		LNX1_HUMAN (2-331): 9.08e-20: 96.1: 14.75
+	Hs
		253559 CAPON_HUMAN (21-284): 6.11e-38: 150: 14.53		SCRIB_HUMAN (240-454): 4.24e-17: 88.3: 17.27