Interactor 1: METK1 (Q00266)
S-adenosylmethionine synthase isoform type-1 (AdoMet synthase 1) (EC 2.5.1.6) (Methionine adenosyltransferase 1) (MAT 1) (Methionine adenosyltransferase I/III) (MAT-I/III)
Gene: MAT1A

Interactor 2: MAT2B (Q9NZL9)
Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) (MAT II beta) (Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase)
Gene: MAT2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RmlD_sub_bind~S-AdoMet_synt_C, RmlD_sub_bind~S-AdoMet_synt_M
Common GO terms GO:0005829 - cytosol
GO:0006556 - S-adenosylmethionine biosynthetic process
GO:0006730 - one-carbon metabolic process
GO:0048269 - methionine adenosyltransferase complex
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 395
Hs

1 334
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024