HitPredict

Interactor 1: CDK5 (Q00535)
Cyclin-dependent kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Cyclin-dependent-like kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)
Gene: CDK5

Interactor 2: CK5P2 (Q96SN8)
CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215)
Gene: CDK5RAP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10915792
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030054 - cell junction
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 292 Hs			1 1893
+	Hs
		528401 CDK2_HUMAN (1-292): 2.7e-143: 406: 59.39		MYH8_HUMAN (923-1875): 1.35e-32: 141: 11.98
+	Hs
		528405 CDK3_HUMAN (1-291): 4.77e-141: 401: 61.30		MYH8_HUMAN (923-1875): 1.35e-32: 141: 11.98
+	Hs
		551610 CDK2_HUMAN (1-292): 2.7e-143: 406: 59.39		DESP_HUMAN (35-576): 3.93e-27: 123: 16.16
+	Hs
		625176 CDK2_HUMAN (1-292): 2.7e-143: 406: 59.39		MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17
+	Hs
		960128 CDK3_HUMAN (1-291): 4.77e-141: 401: 61.30		MYH2_HUMAN (1169-1882): 5.05e-23: 109: 10.61
+	Hs
		414704 CDK1_HUMAN (1-289): 1.13e-134: 384: 56.01		TPR_HUMAN (1-749): 1.76e-27: 124: 10.95
+	Hs
		414713 CDK1_HUMAN (1-289): 1.13e-134: 384: 56.01		DESP_HUMAN (35-576): 3.93e-27: 123: 16.16
+	Hs
		518840 CDK7_HUMAN (2-292): 2.63e-127: 367: 45.24		TPR_HUMAN (1-749): 1.76e-27: 124: 10.95
+	Hs
		960129 CDK3_HUMAN (1-291): 4.77e-141: 401: 61.30		MYH13_HUMAN (50-537): 8.88e-17: 89.3: 13.44
+	Hs
		625530 CDK2_HUMAN (1-292): 2.7e-143: 406: 59.39		MY18A_HUMAN (124-716): 5.89e-15: 83.4: 16.56
+	Hs
		625177 CDK2_HUMAN (1-292): 2.7e-143: 406: 59.39		MYH10_HUMAN (1278-1866): 8.19e-15: 83: 11.48
+	Hs
		522604 CDK3_HUMAN (1-291): 4.77e-141: 401: 61.30		MYH7_HUMAN (36-501): 1e-15: 86.1: 9.77
+	Hs
		724717 CDK7_HUMAN (2-292): 2.63e-127: 367: 45.24		MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17
+	Hs
		522542 CDK3_HUMAN (1-291): 4.77e-141: 401: 61.30		MYH1_HUMAN (884-1666): 1.1e-12: 76.1: 12.50
+	Hs
		528368 CDK3_HUMAN (1-291): 4.77e-141: 401: 61.30		MYH6_HUMAN (864-1654): 3.35e-11: 71.1: 11.49
+	Hs
		502908 CDK3_HUMAN (1-291): 4.77e-141: 401: 61.30		MYH3_HUMAN (938-1610): 2.46e-10: 68.4: 9.82
+	Hs
		148286 CDK1_HUMAN (1-289): 1.13e-134: 384: 56.01		CTRO_HUMAN (456-1261): 1.07e-13: 79.2: 12.65
+	Hs
		725114 CDK7_HUMAN (2-292): 2.63e-127: 367: 45.24		MYH10_HUMAN (1278-1866): 8.19e-15: 83: 11.48