Interactor 1: NDP (Q00604)
Norrin (Norrie disease protein) (X-linked exudative vitreoretinopathy 2 protein)
Gene: NDP

Interactor 2: FZD4 (Q9ULV1)
Frizzled-4 (Fz-4) (hFz4) (FzE4) (CD antigen CD344)
Gene: FZD4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.90 0.764

The method score is based on:

Property Details
Experiments 15035989, 19837033, 17955262
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, imaging technique
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cys_knot~Fz
Common GO terms GO:0001525 - angiogenesis
GO:0009986 - cell surface
GO:0035426 - extracellular matrix-cell signaling
GO:0042803 - protein homodimerization activity
GO:0045446 - endothelial cell differentiation
and 5 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024