Interactor 1: MDM2 (Q00987)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Interactor 2: DAXX (Q9UER7)
Death domain-associated protein 6 (Daxx) (hDaxx) (ETS1-associated protein 1) (EAP1) (Fas death domain-associated protein)
Gene: DAXX

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.759

The method score is based on:

Property Details
Experiments 18583933, 16845383, 18566590, 15364927, 23405218, 23038753, 28875283, 21134643, 20195357
Identification Methods affinity chromatography technology, pull down, unspecified method, nuclear magnetic resonance, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, display technology
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002039 - p53 binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005829 - cytosol
and 4 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 491
Hs

1 740
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024