HitPredict

Interactor 1: ESMB (Q01069)
Enhancer of split mbeta protein (E(spl)mbeta) (HLH-mbeta) (Split locus enhancer protein mA)
Gene: E(spl)mbeta-HLH

Interactor 2: ESMB (Q01069)
Enhancer of split mbeta protein (E(spl)mbeta) (HLH-mbeta) (Split locus enhancer protein mA)
Gene: E(spl)mbeta-HLH

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.723

The method score is based on:

Property Details
Experiments 9371806, unassigned4
Identification Methods two hybrid, experimental interaction detection
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hairy_orange~Hairy_orange, HLH~HLH
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0002052 - positive regulation of neuroblast proliferation
and 13 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 195
Dm

1 195
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Last updated: 15 Jul 2024