Interactor 1: PFD3 (P61758)
Prefoldin subunit 3 (HIBBJ46) (von Hippel-Lindau-binding protein 1) (VBP-1) (VHL-binding protein 1)
Gene: VBP1

Interactor 2: PFD2 (Q9UHV9)
Prefoldin subunit 2
Gene: PFDN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.980

The method score is based on:

Property Details
Experiments 28514442, 14634002, 32296183, 33961781, 34349018, 35235311, 28524877, 31839598, 24981860, 37071682, 38334954, unassigned1304, 32814053, unassigned3799
Identification Methods affinity chromatography technology, biochemical, two hybrid, cross-linking study, validated two hybrid, two hybrid array, two hybrid pooling approach, anti tag coimmunoprecipitation, two hybrid prey pooling approach
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Prefoldin~Prefoldin_2
Common GO terms GO:0001540 - amyloid-beta binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006457 - protein folding
and 3 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 197
Hs

1 154
+ Hs
+ Dm
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025