HitPredict

Interactor 1: SPTB2 (Q01082)
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)
Gene: SPTBN1

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16159877
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 2364 Hs			1 2752
+	Hs
		963398 SPTB2_HUMAN (1-2364): 0: 751: 100.00		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		963292 SPTB2_HUMAN (1-2364): 0: 751: 100.00		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23
+	Hs
		1068702 PLEC_HUMAN (222-1144): 1.08e-16: 89.7: 11.59		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		521599 ACTN1_HUMAN (28-775): 4.31e-92: 323: 34.25		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		211629 ACTN4_HUMAN (53-525): 6.51e-121: 409: 47.58		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		993278 ACTN3_HUMAN (41-776): 4.93e-97: 338: 33.73		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		521586 ACTN1_HUMAN (28-775): 4.31e-92: 323: 34.25		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Mm
		561172 SPTN1_MOUSE (266-1626): 2.72e-51: 203: 18.87		ANK2_MOUSE (875-2680): 3.07e-20: 101: 14.69
+	Hs
		944680 PLEC_HUMAN (222-1144): 1.08e-16: 89.7: 11.59		MAP1A_HUMAN (170-2540): 2.1e-44: 181: 9.15
+	Hs
		506836 SPTB1_HUMAN (1359-2356): 5.1e-25: 117: 13.42		DIDO1_HUMAN (13-1216): 9.01e-11: 70.1: 10.22
+	Rn
		251022 PLEC_RAT (222-1112): 2.48e-16: 88.6: 10.66		ANK3_RAT (710-1636): 6.15e-18: 94.1: 16.74
+	Hs
		513849 DMD_HUMAN (234-2093): 2.37e-21: 105: 9.67		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23
+	Hs
		965102 SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23
+	Hs
		965174 MACF1_HUMAN (687-1920): 4.98e-16: 87.6: 12.23		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23
+	Hs
		164604 SPTN2_HUMAN (1661-2338): 1.76e-11: 72.4: 15.10		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23