HitPredict

Interactor 1: E2F1 (Q01094)
Transcription factor E2F1 (E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1) (Retinoblastoma-binding protein 3) (RBBP-3) (pRB-binding protein E2F-1)
Gene: E2F1

Interactor 2: MCPH1 (Q8NEM0)
Microcephalin
Gene: MCPH1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.677

Property	Details
Experiments	18660752, 23697381, 23001041
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, bimolecular fluorescence complementation, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005813 - centrosome
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 835
+	Hs
		1051774 E2F2_HUMAN (40-432): 7.31e-121: 360: 41.75		MCPH1_HUMAN (1-835): 0: 1765: 100.00