HitPredict

Interactor 1: FOXK2 (Q01167)
Forkhead box protein K2 (G/T-mismatch specific binding protein) (nGTBP) (Interleukin enhancer-binding factor 1)
Gene: FOXK2

Interactor 2: ING1 (Q9UK53)
Inhibitor of growth protein 1
Gene: ING1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	25609649, 33961781
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 660 Hs			1 422
+	Hs
		952894 FOXK1_HUMAN (34-627): 5.33e-81: 273: 53.57		ING1_HUMAN (1-422): 0: 572: 100.00
+	Hs
		964252 FOXK2_HUMAN (35-660): 2.35e-129: 397: 100.00		ING2_HUMAN (158-419): 3.18e-61: 201: 51.91
+	Hs
		964171 FOXK2_HUMAN (35-660): 2.35e-129: 397: 100.00		BPTF_HUMAN (162-401): 2.27e-37: 147: 18.40
+	Hs
		964181 FOXK2_HUMAN (35-660): 2.35e-129: 397: 100.00		CHD4_HUMAN (246-417): 2.51e-21: 99.2: 19.89
+	Hs
		952872 FOXK1_HUMAN (34-627): 5.33e-81: 273: 53.57		ING2_HUMAN (158-419): 3.18e-61: 201: 51.91
+	Ce
		184246 FOXO_CAEEL (212-554): 4.2e-55: 198: 19.02		NU301_CAEEL (231-418): 3.45e-31: 128: 17.33
+	Hs
		126461 FOXE1_HUMAN (212-538): 1.48e-54: 192: 25.81		CHD4_HUMAN (246-417): 2.51e-21: 99.2: 19.89
+	Hs
		1021109 FOXC1_HUMAN (197-406): 2.04e-52: 191: 32.04		CHD4_HUMAN (246-417): 2.51e-21: 99.2: 19.89
+	Hs
		877612 FOXG1_HUMAN (167-553): 4.56e-50: 183: 21.68		CHD4_HUMAN (246-417): 2.51e-21: 99.2: 19.89
+	Hs
		877716 FOXA1_HUMAN (147-565): 2.65e-46: 172: 19.91		CHD3_HUMAN (246-406): 1.87e-24: 108: 18.79
+	Hs
		877733 FOXA1_HUMAN (147-565): 2.65e-46: 172: 19.91		CHD4_HUMAN (246-417): 2.51e-21: 99.2: 19.89