HitPredict

Interactor 1: RUNX1 (Q01196)
Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit)
Gene: RUNX1

Interactor 2: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28533407
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 453 Hs			1 551
+	Hs
		846932 RUNX1_HUMAN (1-453): 0: 702: 100.00		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		964440 RUNX1_HUMAN (1-453): 0: 702: 100.00		SC31B_HUMAN (126-488): 7.13e-37: 148: 14.93
+	Hs
		964316 RUNX1_HUMAN (1-453): 0: 702: 100.00		PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51
+	Hs
		516472 RUNX1_HUMAN (1-453): 0: 702: 100.00		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Mm
		1111919 Q3UM65_MOUSE (6-453): 0: 679: 95.76		SMCA4_MOUSE (172-423): 2.26e-10: 65.7: 12.30