HitPredict

Interactor 1: NOP3 (Q01560)
Serine/arginine (SR)-type shuttling mRNA binding protein NPL3 (Mitochondrial targeting suppressor 1 protein) (Nuclear polyadenylated RNA-binding protein 1) (Nuclear protein localization protein 3) (Polyadenylate-binding protein NPL3)
Gene: NPL3

Interactor 2: AIR2 (Q12476)
Protein AIR2 (Arginine methyltransferase-interacting RING finger protein 2)
Gene: AIR2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.50	0.651

Property	Details
Experiments	11805837, 32561742, 10896665, 18077427, 23918811
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 414 Sc			1 344
+	Sc
		774814 NOP3_YEAST (1-414): 6.5e-65: 215: 100.00		AIR1_YEAST (4-332): 1.22e-79: 249: 45.12
+	Sc
		376983 PABP_YEAST (202-285): 1.62e-11: 68: 18.39		AIR2_YEAST (1-344): 2.7e-104: 311: 100.00
+	Sc
		376814 PABP_YEAST (202-285): 1.62e-11: 68: 18.39		AIR1_YEAST (4-332): 1.22e-79: 249: 45.12
+	Sc
		865289 NOP3_YEAST (1-414): 6.5e-65: 215: 100.00		GIS2_YEAST (99-234): 1.95e-11: 63.4: 15.03
+	Hs
		1232768 RBM4B_HUMAN (199-278): 3.99e-09: 59.9: 16.25		ZCHC7_HUMAN (51-344): 2.5e-61: 206: 20.79
+	Hs
		1029124 SRSF6_HUMAN (126-274): 1.55e-44: 159: 25.82		ZCHC3_HUMAN (43-131): 1e-21: 96.9: 28.89
+	Hs
		992957 SRSF1_HUMAN (117-264): 1.06e-42: 152: 26.40		ZCHC3_HUMAN (43-131): 1e-21: 96.9: 28.89
+	Hs
		1028841 SRSF5_HUMAN (122-272): 1.04e-33: 128: 25.00		ZCHC3_HUMAN (43-131): 1e-21: 96.9: 28.89
+	Hs
		914744 SRSF6_HUMAN (126-274): 1.55e-44: 159: 25.82		CNBP_HUMAN (123-232): 1.25e-09: 58.8: 12.75
+	Hs
		1020336 ELAV2_HUMAN (106-182): 7.18e-13: 71.4: 17.65		ZCHC3_HUMAN (43-131): 1e-21: 96.9: 28.89
+	Hs
		516714 PABP1_HUMAN (190-285): 3.21e-12: 70.3: 15.15		ZCHC3_HUMAN (43-131): 1e-21: 96.9: 28.89
+	Sc
		633976 GBP2_YEAST (124-272): 1.18e-16: 83.1: 25.86		GIS2_YEAST (99-234): 1.95e-11: 63.4: 15.03
+	Sc
		376882 PABP_YEAST (202-285): 1.62e-11: 68: 18.39		GIS2_YEAST (99-234): 1.95e-11: 63.4: 15.03
+	Hs
		914823 PABP3_HUMAN (190-285): 3.3e-10: 63.7: 13.13		CNBP_HUMAN (123-232): 1.25e-09: 58.8: 12.75