HitPredict

Interactor 1: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Interactor 2: DUX4 (Q9UBX2)
Double homeobox protein 4 (Double homeobox protein 10)
Gene: DUX4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.516

Property	Details
Experiments	26816005
Identification Methods	pull down
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 463 Hs			1 424
+	Mm
		966056 HNRPK_MOUSE (1-463): 3.38e-139: 409: 100.00		Q8VD35_MOUSE (1-95): 1.43e-10: 63.9: 31.58
+	Hs
		1453299 IF2B1_HUMAN (1-461): 7.01e-66: 223: 14.71		DUX4_HUMAN (1-424): 4.08e-60: 203: 100.00
+	Hs
		92335 D3DTW3_HUMAN (1-461): 1.58e-63: 213: 14.71		DUX4_HUMAN (1-424): 4.08e-60: 203: 100.00
+	Hs
		1147012 PCBP2_HUMAN (127-222): 1.6e-12: 70.8: 29.17		DUX4_HUMAN (1-424): 4.08e-60: 203: 100.00
+	Hs
		1146859 PCBP1_HUMAN (7-111): 7.46e-12: 68.5: 14.95		DUX4_HUMAN (1-424): 4.08e-60: 203: 100.00
+	Hs
		1200474 Q53SS8_HUMAN (7-111): 7.46e-12: 68.5: 14.95		DUX4_HUMAN (1-424): 4.08e-60: 203: 100.00
+	Hs
		135373 IF2B3_HUMAN (193-461): 4.23e-09: 60.7: 13.99		DUX4_HUMAN (1-424): 4.08e-60: 203: 100.00
+	Hs
		1146924 PCBP2_HUMAN (127-222): 1.6e-12: 70.8: 29.17		DUX4C_HUMAN (1-375): 1.82e-43: 157: 93.87
+	Hs
		1200473 Q53SS8_HUMAN (7-111): 7.46e-12: 68.5: 14.95		DUX4C_HUMAN (1-375): 1.82e-43: 157: 93.87
+	Mm
		949832 PCBP1_MOUSE (7-111): 7.46e-12: 68.5: 14.95		Q8VD35_MOUSE (1-95): 1.43e-10: 63.9: 31.58