HitPredict

Interactor 1: XPC (Q01831)
DNA repair protein complementing XP-C cells (Xeroderma pigmentosum group C-complementing protein) (p125)
Gene: XPC

Interactor 2: DDB2 (Q92466)
DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2)
Gene: DDB2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.714

The method score is based on:

Property	Details
Experiments	28760956, 15882621, 27203177, 22039351, 23319653
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003684 - damaged DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006281 - DNA repair and 4 others more... GO:0006289 - nucleotide-excision repair GO:0044877 - protein-containing complex binding GO:0070914 - UV-damage excision repair GO:0090734 - site of DNA damage
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	940
Hs

1	427

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024