HitPredict

Interactor 1: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Interactor 2: TFG (Q92734)
Protein TFG (TRK-fused gene protein)
Gene: TFG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	25416956, 24999758
Identification Methods	two hybrid, proximity labelling technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 656 Hs			1 400
+	Hs
		118589 EYA2_HUMAN (27-278): 1.48e-18: 91.3: 20.16		TFG_HUMAN (1-400): 4.64e-79: 250: 100.00
+	Hs
		967541 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		PCLO_HUMAN (69-398): 8.34e-15: 78.8: 18.07
+	Hs
		124033 RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05		SPT5H_HUMAN (105-292): 2.84e-09: 61.1: 9.62
+	Hs
		867093 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		SC24C_HUMAN (97-340): 3.76e-09: 60.7: 14.69
+	Hs
		297856 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		SC24D_HUMAN (161-366): 7.9e-09: 59.6: 15.94
+	Hs
		123820 EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02		SPT5H_HUMAN (105-292): 2.84e-09: 61.1: 9.62
+	Hs
		123866 FUS_HUMAN (55-545): 1.15e-31: 131: 30.35		SPT5H_HUMAN (105-292): 2.84e-09: 61.1: 9.62
+	Hs
		123790 HTSF1_HUMAN (310-448): 3.35e-28: 122: 20.55		SPT5H_HUMAN (105-292): 2.84e-09: 61.1: 9.62