HitPredict

Interactor 1: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Interactor 2: SH24A (Q9H788)
SH2 domain-containing protein 4A (Protein SH(2)A) (Protein phosphatase 1 regulatory subunit 38)
Gene: SH2D4A

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.97	0.60	0.763

Property	Details
Experiments	25416956, 26496610, 27880917, 27173435, 17353931, 28330616, 27107012, 26186194, 28514442, 32296183, 33961781, unassigned1304, unassigned3799
Identification Methods	two hybrid, affinity chromatography technology, proximity labelling technology, two hybrid prey pooling approach, two hybrid array, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, barcode fusion genetics two hybrid, validated two hybrid, tandem affinity purification and 1 others more... pull down
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 327 Hs			1 454
+	Hs
		967974 PP1A_HUMAN (1-326): 0: 576: 88.79		SH24A_HUMAN (1-454): 1.01e-130: 387: 100.00
+	Hs
		786855 PP1G_HUMAN (1-327): 0: 569: 86.89		SH24A_HUMAN (1-454): 1.01e-130: 387: 100.00
+	Mm
		968501 PP1B_MOUSE (1-327): 0: 597: 100.00		GRB2_MOUSE (310-454): 2.56e-41: 148: 24.83
+	Hs
		968243 PP1B_HUMAN (1-327): 0: 597: 100.00		GRB2_HUMAN (310-454): 8.07e-41: 147: 24.83
+	Hs
		967653 PP1A_HUMAN (1-326): 0: 576: 88.79		GRB2_HUMAN (310-454): 8.07e-41: 147: 24.83
+	Hs
		786521 PP1G_HUMAN (1-327): 0: 569: 86.89		GRB2_HUMAN (310-454): 8.07e-41: 147: 24.83