HitPredict

Interactor 1: NAAA (Q02083)
N-acylethanolamine-hydrolyzing acid amidase (EC 3.5.1.60) (Acid ceramidase-like protein) (Acylsphingosine deacylase NAAA) (EC 3.5.1.23) (N-acylsphingosine amidohydrolase-like) (ASAH-like protein) [Cleaved into: N-acylethanolamine-hydrolyzing acid amidase subunit alpha; N-acylethanolamine-hydrolyzing acid amidase subunit beta]
Gene: NAAA

Interactor 2: ARSK (Q6UWY0)
Arylsulfatase K (ASK) (EC 3.1.6.1) (Glucuronate-2-sulfatase) (EC 3.1.6.18) (Telethon sulfatase)
Gene: ARSK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005764 - lysosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 359 Hs			1 536
+	Hs
		968870 NAAA_HUMAN (1-359): 0: 534: 100.00		SULF2_HUMAN (4-440): 5.41e-112: 354: 21.43
+	Hs
		546604 NAAA_HUMAN (1-359): 0: 534: 100.00		ARSA_HUMAN (30-459): 7.26e-114: 348: 20.64
+	Hs
		550462 NAAA_HUMAN (1-359): 0: 534: 100.00		ARSB_HUMAN (20-476): 4.3e-113: 347: 16.21
+	Hs
		709245 NAAA_HUMAN (1-359): 0: 534: 100.00		GALNS_HUMAN (14-491): 3.19e-101: 316: 18.01
+	Hs
		606877 NAAA_HUMAN (1-359): 0: 534: 100.00		IDS_HUMAN (3-391): 1.28e-93: 297: 22.35
+	Hs
		849834 NAAA_HUMAN (1-359): 0: 534: 100.00		SPHM_HUMAN (8-469): 1.55e-85: 275: 21.90