Interactor 1: KPCE (Q02156)
Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)
Gene: PRKCE

Interactor 2: GRP3 (Q8IV61)
Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1)
Gene: RASGRP3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 15213298
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~C1_1, C1_1~C2, C1_1~Pkinase, EF-hand_7~Pkinase
Common GO terms GO:0000165 - MAPK cascade
GO:0005886 - plasma membrane
GO:0048471 - perinuclear region of cytoplasm
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 737
Hs

1 690
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Rn
+ Hs
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Last updated: 15 Jul 2024