HitPredict

Interactor 1: IRF8 (Q02556)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (H-ICSBP) (ICSBP)
Gene: IRF8

Interactor 2: DHX58 (Q96C10)
ATP-dependent RNA helicase DHX58 (EC 3.6.4.13) (ATP-dependent helicase LGP2) (Protein D11Lgp2 homolog) (RIG-I-like receptor 3) (RLR-3) (RIG-I-like receptor LGP2) (RLR)
Gene: DHX58

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22096565
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 426 Hs			1 678
+	Hs
		971753 IRF8_HUMAN (1-426): 0: 587: 100.00		IFIH1_HUMAN (1-674): 7.37e-119: 381: 40.39
+	Mm
		619027 IRF8_MOUSE (1-426): 0: 579: 89.67		IFIH1_MOUSE (1-674): 1.33e-119: 383: 39.75
+	Hs
		321899 IRF3_HUMAN (9-399): 1.44e-139: 407: 26.68		RIGI_HUMAN (1-666): 1.75e-101: 333: 29.89
+	Mm
		936899 IRF3_MOUSE (9-399): 7.76e-136: 397: 24.57		RIGI_MOUSE (1-666): 3.84e-103: 337: 28.88
+	Hs
		1071078 IRF4_HUMAN (6-386): 9.59e-150: 434: 43.96		CHD7_HUMAN (2-593): 4.96e-79: 277: 12.36
+	Hs
		846780 IRF4_HUMAN (6-386): 9.59e-150: 434: 43.96		SMCA2_HUMAN (2-592): 7.46e-73: 259: 13.25
+	Hs
		321920 IRF7_HUMAN (12-385): 3.06e-114: 345: 21.91		RIGI_HUMAN (1-666): 1.75e-101: 333: 29.89
+	Hs
		1056467 IRF3_HUMAN (9-399): 1.44e-139: 407: 26.68		CHD8_HUMAN (2-605): 2.72e-75: 266: 12.29
+	Hs
		134041 IRF3_HUMAN (9-399): 1.44e-139: 407: 26.68		DDX3X_HUMAN (146-516): 5.67e-56: 203: 16.67
+	Hs
		321869 IRF1_HUMAN (9-187): 2.59e-62: 206: 33.69		RIGI_HUMAN (1-666): 1.75e-101: 333: 29.89
+	Hs
		501017 IRF1_HUMAN (9-187): 2.59e-62: 206: 33.69		SMCA2_HUMAN (2-592): 7.46e-73: 259: 13.25