HitPredict

Interactor 1: CACB1 (Q02641)
Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1)
Gene: CACNB1

Interactor 2: CAC1C (Q13936)
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)
Gene: CACNA1C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.571

The method score is based on:

Property Details
Experiments 18535142, 37207277
Identification Methods anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005245 - voltage-gated calcium channel activity
GO:0005886 - plasma membrane
GO:0005891 - voltage-gated calcium channel complex
GO:0008331 - high voltage-gated calcium channel activity
GO:0070588 - calcium ion transmembrane transport
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 598
Hs

1 2221
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Mm
+ Rn
+ Mm
+ Mm
+ Oc
+ Oc
+ Mm
+ Mm
+ Mm
+ Oc
+ Mm
+ Hs
+ Mm
+ Oc
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024