HitPredict

Interactor 1: PAX2 (Q02962)
Paired box protein Pax-2
Gene: PAX2

Interactor 2: TLE1 (Q04724)
Transducin-like enhancer protein 1 (E(Sp1) homolog) (Enhancer of split groucho-like protein 1) (ESG1)
Gene: TLE1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 417 Hs			1 770
+	Hs
		973843 PAX2_HUMAN (1-417): 2.32e-119: 355: 100.00		TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42
+	Hs
		641377 PAX6_HUMAN (13-417): 4.77e-92: 285: 32.35		TLE1_HUMAN (1-770): 0: 594: 100.00
+	Hs
		971652 PAX5_HUMAN (1-417): 1.56e-97: 298: 62.20		TLE4_HUMAN (1-770): 0: 562: 86.27
+	Hs
		620142 PAX7_HUMAN (16-410): 3.06e-80: 257: 31.83		TLE1_HUMAN (1-770): 0: 594: 100.00
+	Hs
		641379 PAX6_HUMAN (13-417): 4.77e-92: 285: 32.35		TLE4_HUMAN (1-770): 0: 562: 86.27
+	Hs
		980588 PAX8_HUMAN (9-415): 2.13e-71: 233: 47.13		TLE1_HUMAN (1-770): 0: 594: 100.00
+	Mm
		623700 PAX3_MOUSE (16-411): 1.65e-80: 257: 33.25		TLE4_MOUSE (1-770): 0: 563: 86.27
+	Hs
		620144 PAX7_HUMAN (16-410): 3.06e-80: 257: 31.83		TLE4_HUMAN (1-770): 0: 562: 86.27
+	Hs
		641378 PAX6_HUMAN (13-417): 4.77e-92: 285: 32.35		TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42
+	Hs
		980927 PAX8_HUMAN (9-415): 2.13e-71: 233: 47.13		TLE4_HUMAN (1-770): 0: 562: 86.27
+	Hs
		620143 PAX7_HUMAN (16-410): 3.06e-80: 257: 31.83		TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42
+	Hs
		980733 PAX8_HUMAN (9-415): 2.13e-71: 233: 47.13		TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42
+	Hs
		973846 PAX2_HUMAN (1-417): 2.32e-119: 355: 100.00		TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50
+	Hs
		641385 PAX6_HUMAN (13-417): 4.77e-92: 285: 32.35		TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50
+	Hs
		620146 PAX7_HUMAN (16-410): 3.06e-80: 257: 31.83		TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50
+	Hs
		988754 PAX8_HUMAN (9-415): 2.13e-71: 233: 47.13		TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50
+	Hs
		245563 PAX6_HUMAN (13-417): 4.77e-92: 285: 32.35		TBL1X_HUMAN (569-769): 5.32e-46: 175: 16.51
+	Hs
		245559 PAX7_HUMAN (16-410): 3.06e-80: 257: 31.83		TBL1X_HUMAN (569-769): 5.32e-46: 175: 16.51
+	Hs
		620138 PAX7_HUMAN (16-410): 3.06e-80: 257: 31.83		WDR5_HUMAN (655-769): 2.57e-36: 141: 21.37
+	Hs
		245583 PAX9_HUMAN (13-246): 2.63e-54: 185: 45.11		TBL1X_HUMAN (569-769): 5.32e-46: 175: 16.51