HitPredict

Interactor 1: DYST (Q03001)
Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)
Gene: DST

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 7570 Hs			1 530
+	Hs
		369446 DYST_HUMAN (1-7570): 0: 2600: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		521591 ACTN1_HUMAN (3770-4283): 1.06e-26: 123: 10.00		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269937 MACF1_HUMAN (351-1936): 4.95e-21: 105: 11.05		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		164649 SPTN2_HUMAN (5708-7163): 4.91e-17: 92.5: 14.91		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		809148 UTRN_HUMAN (264-1530): 1.26e-14: 84.8: 9.65		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1045473 SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1263700 SYNE2_HUMAN (282-1774): 1.65e-12: 77.9: 8.82		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1068618 PLEC_HUMAN (1777-1974): 1.7e-12: 77.5: 19.19		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		368893 ACTN1_HUMAN (3770-4283): 1.06e-26: 123: 10.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		993279 ACTN3_HUMAN (453-929): 1.33e-11: 74.3: 10.26		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369420 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370715 MACF1_HUMAN (351-1936): 4.95e-21: 105: 11.05		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369158 UTRN_HUMAN (264-1530): 1.26e-14: 84.8: 9.65		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369568 SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369641 PLEC_HUMAN (1777-1974): 1.7e-12: 77.5: 19.19		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		513834 DMD_HUMAN (383-1643): 8.98e-27: 124: 11.75		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		510045 MACF1_HUMAN (351-1936): 4.95e-21: 105: 11.05		ERR1_HUMAN (85-497): 1.88e-112: 342: 35.65
+	Hs
		521532 ACTN1_HUMAN (3770-4283): 1.06e-26: 123: 10.00		NR1H3_HUMAN (65-499): 1.77e-104: 322: 20.97
+	Hs
		320227 SPTN4_HUMAN (6019-7220): 1.47e-12: 77.8: 14.47		ERR2_HUMAN (69-499): 5.86e-109: 333: 31.57
+	Hs
		377536 SYNE2_HUMAN (282-1774): 1.65e-12: 77.9: 8.82		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64