HitPredict

Interactor 1: DYST (Q03001)
Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein)
Gene: DST

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 7570 Hs			1 779
+	Hs
		513893 DMD_HUMAN (383-1643): 8.98e-27: 124: 11.75		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		521613 ACTN1_HUMAN (3770-4283): 1.06e-26: 123: 10.00		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		963417 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1331636 MACF1_HUMAN (351-1936): 4.95e-21: 105: 11.05		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		809171 UTRN_HUMAN (264-1530): 1.26e-14: 84.8: 9.65		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1045520 SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1068666 PLEC_HUMAN (1777-1974): 1.7e-12: 77.5: 19.19		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		885313 EPIPL_HUMAN (1651-1891): 1.02e-10: 71.7: 20.73		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1059270 GOGB1_HUMAN (1119-1866): 1.3e-10: 71.3: 6.59		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		521561 ACTN1_HUMAN (3770-4283): 1.06e-26: 123: 10.00		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		513853 DMD_HUMAN (383-1643): 8.98e-27: 124: 11.75		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Mm
		1143715 SPTB2_MOUSE (6042-7200): 1.95e-19: 100: 13.42		CNKR2_MOUSE (1-468): 7.51e-48: 185: 14.40
+	Hs
		513896 DMD_HUMAN (383-1643): 8.98e-27: 124: 11.75		PKHA2_HUMAN (1-258): 2.68e-38: 149: 15.90
+	Hs
		963422 SPTB2_HUMAN (5709-7570): 7.99e-22: 108: 12.95		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		57984 ACTN3_HUMAN (453-929): 1.33e-11: 74.3: 10.26		A2RRN7_HUMAN (57-428): 4.21e-47: 181: 12.44
+	Hs
		993303 ACTN3_HUMAN (453-929): 1.33e-11: 74.3: 10.26		CAPS1_HUMAN (11-428): 3.69e-46: 180: 11.26
+	Hs
		521574 ACTN1_HUMAN (3770-4283): 1.06e-26: 123: 10.00		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		809176 UTRN_HUMAN (264-1530): 1.26e-14: 84.8: 9.65		PKHA2_HUMAN (1-258): 2.68e-38: 149: 15.90
+	Hs
		1045526 SPTN1_HUMAN (269-874): 2.44e-13: 80.3: 13.42		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		1068669 PLEC_HUMAN (1777-1974): 1.7e-12: 77.5: 19.19		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61