HitPredict

Interactor 1: CAV1 (Q03135)
Caveolin-1
Gene: CAV1

Interactor 2: RHOH (Q15669)
Rho-related GTP-binding protein RhoH (GTP-binding protein TTF) (Translocation three four protein)
Gene: RHOH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0019901 - protein kinase binding GO:0031267 - small GTPase binding GO:0031410 - cytoplasmic vesicle
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 178 Hs			1 191
+	Hs
		436263 CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00		RHOC_HUMAN (6-185): 6.48e-85: 250: 42.25
+	Hs
		915622 CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00		RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93
+	Hs
		925216 CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00		RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09
+	Mm
		835141 CAV1_MOUSE (1-178): 4.63e-108: 308: 94.94		RAC1_MOUSE (2-191): 2.63e-75: 226: 39.09
+	Hs
		564489 CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00		RHOQ_HUMAN (5-190): 8.15e-74: 222: 39.49
+	Hs
		893921 CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00		CDC42_HUMAN (2-181): 1.52e-73: 221: 42.25
+	Hs
		545335 CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00		RAC2_HUMAN (2-191): 1.96e-72: 218: 38.07
+	Hs
		892328 CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00		RAC3_HUMAN (2-171): 3.86e-72: 218: 41.81
+	Hs
		950938 CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00		RHOG_HUMAN (2-191): 2.32e-71: 216: 37.56
+	Hs
		900399 CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00		RHOA_HUMAN (6-191): 8.9e-71: 214: 39.38
+	Hs
		848534 CAV2_HUMAN (53-177): 5.1e-59: 183: 40.80		RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93
+	Hs
		848537 CAV2_HUMAN (53-177): 5.1e-59: 183: 40.80		RHOG_HUMAN (2-191): 2.32e-71: 216: 37.56