HitPredict

Interactor 1: PKH3 (Q03306)
Serine/threonine-protein kinase PKH3 (EC 2.7.11.1) (Pkb-activating kinase homolog 3)
Gene: PKH3

Interactor 2: MYO5 (Q04439)
Myosin-5 (Actin-dependent myosin-I MYO5) (Class I unconventional myosin MYO5) (Type I myosin MYO5)
Gene: MYO5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	19841731, 14737190
Identification Methods	two hybrid, peptide array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 898 Sc			1 1219
+	At
		98846 KIN10_ARATH (10-426): 8.35e-135: 414: 19.00		MYO17_ARATH (6-1105): 0: 1111: 27.49
+	Hs
		728513 SIK2_HUMAN (1-773): 3.74e-134: 426: 16.00		MYH11_HUMAN (5-1118): 0: 1018: 24.03
+	Hs
		725010 SIK2_HUMAN (1-773): 3.74e-134: 426: 16.00		MYH9_HUMAN (7-1119): 0: 1017: 23.96
+	Hs
		725242 SIK2_HUMAN (1-773): 3.74e-134: 426: 16.00		MYH10_HUMAN (2-1099): 0: 1013: 24.07
+	Hs
		681696 AKT1_HUMAN (3-364): 8.2e-138: 421: 24.05		MYH9_HUMAN (7-1119): 0: 1017: 23.96
+	Hs
		568567 KAPCA_HUMAN (3-328): 9.35e-132: 400: 26.13		MYH9_HUMAN (7-1119): 0: 1017: 23.96
+	Hs
		568568 KAPCA_HUMAN (3-328): 9.35e-132: 400: 26.13		MYH10_HUMAN (2-1099): 0: 1013: 24.07
+	Hs
		1344754 SNRK_HUMAN (11-488): 2.57e-117: 377: 21.77		MYH2_HUMAN (5-830): 0: 1006: 31.42
+	Hs
		522572 SNRK_HUMAN (11-488): 2.57e-117: 377: 21.77		MYH1_HUMAN (5-830): 0: 1002: 30.57
+	Sc
		976283 PKH1_YEAST (10-300): 1.54e-62: 228: 43.69		MYO5_YEAST (1-1219): 0: 1126: 100.00
+	Hs
		116964 SGK1_HUMAN (2-303): 8.7e-111: 348: 30.72		MYH1_HUMAN (5-830): 0: 1002: 30.57
+	Hs
		528359 KAPCB_HUMAN (2-298): 8.41e-109: 340: 29.14		MYH6_HUMAN (5-830): 0: 1008: 30.73
+	Hs
		610795 KAPCB_HUMAN (2-298): 8.41e-109: 340: 29.14		MYH2_HUMAN (5-830): 0: 1006: 31.42
+	Hs
		522538 KAPCB_HUMAN (2-298): 8.41e-109: 340: 29.14		MYH1_HUMAN (5-830): 0: 1002: 30.57
+	Hs
		610802 KAPCB_HUMAN (2-298): 8.41e-109: 340: 29.14		MYH4_HUMAN (5-818): 0: 1002: 31.11
+	Sc
		979578 PKH2_YEAST (5-300): 4.71e-56: 212: 41.75		MYO5_YEAST (1-1219): 0: 1126: 100.00
+	Hs
		117850 KS6B2_HUMAN (4-432): 9.19e-133: 408: 22.22		MYO1C_HUMAN (31-736): 0: 570: 41.82
+	Hs
		214695 AKT3_HUMAN (4-365): 5.72e-140: 426: 26.02		MYO1B_HUMAN (36-730): 5.19e-171: 538: 39.72
+	Hs
		682219 AKT2_HUMAN (3-349): 2.35e-139: 425: 24.58		MYO5A_HUMAN (712-1118): 1.31e-10: 68.2: 9.31