HitPredict

Interactor 1: GCN5 (Q03330)
Histone acetyltransferase GCN5 (EC 2.3.1.48) (Histone crotonyltransferase GCN5) (EC 2.3.1.-)
Gene: GCN5

Interactor 2: RSC2 (Q06488)
Chromatin structure-remodeling complex subunit RSC2 (RSC complex subunit RSC2) (Remodel the structure of chromatin complex subunit 2)
Gene: RSC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	21179020
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	Bromodomain~Bromodomain
Common GO terms	GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 439 Sc			1 889
+	Mm
		70940 KAT2B_MOUSE (1-430): 0: 535: 39.59		EP300_MOUSE (4-191): 1.42e-31: 135: 18.75
+	Hs
		998943 KAT2B_HUMAN (2-430): 0: 527: 39.22		EP300_HUMAN (4-191): 1.16e-32: 139: 18.75
+	Sc
		603335 GCN5_YEAST (1-439): 0: 543: 100.00		SNF2_YEAST (8-168): 6.81e-25: 114: 23.93
+	Hs
		846838 KAT2B_HUMAN (2-430): 0: 527: 39.22		SMCA2_HUMAN (9-150): 9.42e-28: 123: 24.07
+	Sc
		728746 GCN5_YEAST (1-439): 0: 543: 100.00		BDF1_YEAST (26-219): 5.23e-19: 94.4: 12.63
+	Sc
		715382 GCN5_YEAST (1-439): 0: 543: 100.00		SPT7_YEAST (158-404): 1.37e-18: 93.5: 11.86
+	Mm
		70941 KAT2A_MOUSE (14-430): 1.8e-168: 495: 37.97		EP300_MOUSE (4-191): 1.42e-31: 135: 18.75
+	Hs
		244733 KAT2A_HUMAN (14-430): 5.17e-171: 502: 38.30		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Sc
		696245 GCN5_YEAST (1-439): 0: 543: 100.00		STH1_YEAST (275-377): 2.49e-11: 69.8: 24.27
+	Sc
		969408 GCN5_YEAST (1-439): 0: 543: 100.00		RSC4_YEAST (34-128): 1.91e-10: 66.7: 27.84
+	Mm
		1337432 KAT2B_MOUSE (1-430): 0: 535: 39.59		KAT2B_MOUSE (12-117): 7.58e-11: 68.3: 25.93
+	Hs
		170259 TIF1A_HUMAN (225-438): 1.14e-49: 183: 22.83		BRD2_HUMAN (2-255): 2.31e-29: 127: 15.89
+	Hs
		170485 TIF1A_HUMAN (225-438): 1.14e-49: 183: 22.83		BRD7_HUMAN (2-258): 1.02e-24: 112: 12.36
+	Hs
		847115 TRI33_HUMAN (225-439): 1.05e-41: 160: 20.65		SMCA4_HUMAN (9-122): 8.4e-29: 126: 29.92
+	Hs
		846897 TRI33_HUMAN (225-439): 1.05e-41: 160: 20.65		SMCA2_HUMAN (9-150): 9.42e-28: 123: 24.07
+	Hs
		245097 TRI33_HUMAN (225-439): 1.05e-41: 160: 20.65		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Mm
		1145011 TIF1A_MOUSE (225-438): 6.05e-49: 181: 22.83		TIF1A_MOUSE (47-133): 1.94e-12: 73.3: 32.97
+	Hs
		170170 TIF1A_HUMAN (225-438): 1.14e-49: 183: 22.83		TIF1A_HUMAN (47-132): 1.21e-11: 71: 32.22
+	Mm
		1145015 TRI33_MOUSE (225-439): 1.79e-42: 162: 21.05		TIF1A_MOUSE (47-133): 1.94e-12: 73.3: 32.97
+	Hs
		170511 TRI33_HUMAN (225-439): 1.05e-41: 160: 20.65		TIF1A_HUMAN (47-132): 1.21e-11: 71: 32.22