HitPredict

Interactor 1: ERCC6 (Q03468)
DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)
Gene: ERCC6

Interactor 2: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31722399
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1493 Hs			1 425
+	Hs
		976441 ERCC6_HUMAN (1-1493): 0: 1168: 100.00		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		1083322 CHD5_HUMAN (300-1446): 0: 783: 19.15		RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00
+	Hs
		1059641 CHD4_HUMAN (303-1439): 0: 766: 18.35		RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00
+	Hs
		1018507 CHD3_HUMAN (303-1446): 0: 759: 19.68		RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00
+	Hs
		658682 SMCA1_HUMAN (369-1372): 0: 700: 20.58		RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00
+	Hs
		229413 SMCA5_HUMAN (368-1383): 0: 698: 20.75		RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00
+	Hs
		997824 CHD5_HUMAN (300-1446): 0: 783: 19.15		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		1018714 CHD3_HUMAN (303-1446): 0: 759: 19.68		NLE1_HUMAN (202-424): 3.82e-45: 164: 21.15
+	Hs
		997936 CHD7_HUMAN (3-1479): 0: 774: 17.81		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		997726 CHD4_HUMAN (303-1439): 0: 766: 18.35		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		997695 CHD3_HUMAN (303-1446): 0: 759: 19.68		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		484255 ERPG3_HUMAN (1-487): 0: 753: 96.12		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		929464 CHD4_HUMAN (303-1439): 0: 766: 18.35		RACK1_HUMAN (213-405): 2.23e-28: 115: 20.41
+	Hs
		929424 CHD3_HUMAN (303-1446): 0: 759: 19.68		RACK1_HUMAN (213-405): 2.23e-28: 115: 20.41
+	Hs
		903234 CHD4_HUMAN (303-1439): 0: 766: 18.35		WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61
+	Hs
		658658 SMCA1_HUMAN (369-1372): 0: 700: 20.58		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		229377 SMCA5_HUMAN (368-1383): 0: 698: 20.75		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		1059830 CHD4_HUMAN (303-1439): 0: 766: 18.35		GRWD1_HUMAN (307-404): 4.14e-14: 75.7: 23.47
+	Ce
		954000 CHD3_CAEEL (245-1380): 0: 684: 18.74		LIN53_CAEEL (1-209): 6.74e-42: 154: 14.16
+	Hs
		903535 CHD8_HUMAN (2-1474): 0: 725: 16.46		WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61