Protein: UBXN4
UBX domain-containing protein 4 (Erasin) (UBX domain-containing protein 2)

Gene: UBXN4
Organism: Homo sapiens
Interactions: 182
UniProt ID: Q92575

Gene Ontology (top 5):
GO:0005635 - nuclear envelope
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0006986 - response to unfolded protein

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

934930

TERA
Transitional endoplasmic reticulum ATPase

9

20

Small-scale

0.973

High

1121132

UBE4A
Ubiquitin conjugation factor E4 A

5

3

High-throughput

0.718

High

1365083

UBQL1
Ubiquilin-1

4

12

Small-scale

0.709

High

1257740

VP13C
Intermembrane lipid transfer protein VPS13C

4

4

High-throughput

0.694

High

1365044

VP13A
Intermembrane lipid transfer protein VPS13A

4

4

High-throughput

0.694

High

1364323

IP6K1
Inositol hexakisphosphate kinase 1

4

0

High-throughput

0.664

High

285702

BAF
Barrier-to-autointegration factor

3

1

High-throughput

0.640

High

1250391

DPP8
Dipeptidyl peptidase 8

3

0

High-throughput

0.638

High

1365054

BC11A
BCL11 transcription factor A

3

0

High-throughput

0.638

High

1365051

UBXN6
UBX domain-containing protein 6

1

10

High-throughput

0.618

High

951311

SC61B
Protein transport protein Sec61 subunit beta

2

2

High-throughput

0.611

High

375788

RASK
GTPase KRas

2

11

High-throughput

0.584

High

698958

CALX
Calnexin

2

1

Small-scale

0.584

High

1365047

SEC62
Translocation protein SEC62

2

2

High-throughput

0.584

High

1365049

DERL1
Derlin-1

2

5

Small-scale

0.584

High

641224

FGFR2
Fibroblast growth factor receptor 2

2

4

High-throughput

0.574

High

396620

ESR1
Estrogen receptor

2

7

High-throughput

0.571

High

1240915

S27A4
Long-chain fatty acid transport protein 4

2

1

High-throughput

0.571

High

530145

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.536

High

1349800

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

1

High-throughput

0.536

High

1365053

DERL2
Derlin-2

1

5

High-throughput

0.536

High

1365079

ATIF1
ATPase inhibitor, mitochondrial

2

2

High-throughput

0.533

High

290256

TM1L1
TOM1-like protein 1

1

0

High-throughput

0.518

High

1099743

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.513

High

1203754

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

1365036

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

1365057

TM134
Transmembrane protein 134

1

0

High-throughput

0.513

High

48724

ESYT2
Extended synaptotagmin-2

1

5

High-throughput

0.479

High

126725

RHOD
Rho-related GTP-binding protein RhoD

1

16

High-throughput

0.479

High

174022

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

8

High-throughput

0.479

High

245506

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

1

High-throughput

0.479

High

291466

NU155
Nuclear pore complex protein Nup155

1

1

High-throughput

0.479

High

326593

MFN2
Mitofusin-2

1

1

High-throughput

0.479

High

348634

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

1

High-throughput

0.479

High

417641

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.479

High

418319

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

3

High-throughput

0.479

High

466391

RHOC
Rho-related GTP-binding protein RhoC

1

12

High-throughput

0.479

High

537619

HSP7C
Heat shock cognate 71 kDa protein

1

5

High-throughput

0.479

High

540595

LAMP1
Lysosome-associated membrane glycoprotein 1

1

6

High-throughput

0.479

High

548357

CP2C9
Cytochrome P450 2C9

1

1

High-throughput

0.479

High

581205

RAC2
Ras-related C3 botulinum toxin substrate 2

1

12

High-throughput

0.479

High

599842

YBOX3
Y-box-binding protein 3

1

1

High-throughput

0.479

High

604134

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

605763

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

4

High-throughput

0.479

High

611263

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

1

High-throughput

0.479

High

631382

RAB5A
Ras-related protein Rab-5A

1

4

High-throughput

0.479

High

634557

LMNB1
Lamin-B1

1

6

High-throughput

0.479

High

635138

ICAL
Calpastatin

1

1

High-throughput

0.479

High

715697

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.479

High

837760

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

1

High-throughput

0.479

High

847630

SSRA
Translocon-associated protein subunit alpha

1

2

High-throughput

0.479

High

880631

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.479

High

894947

EMD
Emerin

1

2

High-throughput

0.479

High

901445

RAB7A
Ras-related protein Rab-7a

1

8

High-throughput

0.479

High

901976

RAB9A
Ras-related protein Rab-9A

1

8

High-throughput

0.479

High

904041

BAP31
B-cell receptor-associated protein 31

1

2

High-throughput

0.479

High

910151

RND2
Rho-related GTP-binding protein RhoN

1

19

High-throughput

0.479

High

939954

TPTE
Putative tyrosine-protein phosphatase TPTE

1

2

High-throughput

0.479

High

941946

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.479

High

953595

RAC3
Ras-related C3 botulinum toxin substrate 3

1

12

High-throughput

0.479

High

954870

PSA6
Proteasome subunit alpha type-6

1

1

Small-scale

0.479

High

955434

CDC42
Cell division control protein 42 homolog

1

12

High-throughput

0.479

High

962333

RHOA
Transforming protein RhoA

1

14

High-throughput

0.479

High

962795

RND3
Rho-related GTP-binding protein RhoE

1

17

High-throughput

0.479

High

967508

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.479

High

975157

ARF6
ADP-ribosylation factor 6

1

3

High-throughput

0.479

High

976460

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.479

High

977783

ACTA
Actin, aortic smooth muscle

1

6

High-throughput

0.479

High

988575

RAC1
Ras-related C3 botulinum toxin substrate 1

1

12

High-throughput

0.479

High

1015643

RHOG
Rho-related GTP-binding protein RhoG

1

12

High-throughput

0.479

High

1027113

REEP5
Receptor expression-enhancing protein 5

1

2

High-throughput

0.479

High

1058561

CKAP4
Cytoskeleton-associated protein 4

1

7

High-throughput

0.479

High

1087224

STX4
Syntaxin-4

1

2

High-throughput

0.479

High

1111633

STIM1
Stromal interaction molecule 1

1

2

High-throughput

0.479

High

1125578

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

3

High-throughput

0.479

High

1145043

RAB35
Ras-related protein Rab-35

1

3

High-throughput

0.479

High

1214537

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

1

High-throughput

0.479

High

1214888

WLS
Protein wntless homolog

1

1

Small-scale

0.479

High

1229014

RNF43
E3 ubiquitin-protein ligase RNF43

1

11

High-throughput

0.479

High

1245106

RHDF2
Inactive rhomboid protein 2

1

2

High-throughput

0.479

High

1252162

SYNE3
Nesprin-3

1

1

High-throughput

0.479

High

1276255

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.479

High

1287395

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

20

High-throughput

0.479

High

1293631

DYR2
Dihydrofolate reductase 2, mitochondrial

1

1

High-throughput

0.479

High

1293792

FBX11
F-box only protein 11

1

4

High-throughput

0.479

High

1309860

TEX2
Testis-expressed protein 2

1

1

High-throughput

0.479

High

1324979

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

2

High-throughput

0.479

High

1333928

DHB11
Estradiol 17-beta-dehydrogenase 11

1

3

High-throughput

0.479

High

1337617

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.479

High

1352326

RHBL4
Rhomboid-related protein 4

1

3

High-throughput

0.479

High

1365033

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

3

High-throughput

0.479

High

1365034

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.479

High

1365035

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

3

High-throughput

0.479

High

1365038

LRC59
Leucine-rich repeat-containing protein 59

1

3

High-throughput

0.479

High

1365041

DNJC1
DnaJ homolog subfamily C member 1

1

7

High-throughput

0.479

High

1365043

PANX1
Pannexin-1

1

1

High-throughput

0.479

High

1365045

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

3

High-throughput

0.479

High

1365048

ESYT1
Extended synaptotagmin-1

1

5

High-throughput

0.479

High

1365052

LNP
Endoplasmic reticulum junction formation protein lunapark

1

2

High-throughput

0.479

High

1365055

DJC25
DnaJ homolog subfamily C member 25

1

7

High-throughput

0.479

High

1365056

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

3

High-throughput

0.479

High

1365058

TMT1A
Thiol S-methyltransferase TMT1A

1

2

High-throughput

0.479

High

1365060

RHOF
Rho-related GTP-binding protein RhoF

1

16

High-throughput

0.479

High

1365062

PXMP2
Peroxisomal membrane protein 2

1

3

High-throughput

0.479

High

1365066

OTULL
Inactive ubiquitin thioesterase OTULINL

1

2

High-throughput

0.479

High

1365069

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

1

High-throughput

0.479

High

1365070

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.479

High

1365074

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.479

High

1365075

SE1L1
Protein sel-1 homolog 1

1

1

Small-scale

0.479

High

1365076

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1365077

SEC63
Translocation protein SEC63 homolog

1

4

High-throughput

0.479

High

1365080

AMFR
E3 ubiquitin-protein ligase AMFR

1

9

Small-scale

0.479

High

1365085

DJC16
DnaJ homolog subfamily C member 16

1

4

High-throughput

0.479

High

1365086

FIS1
Mitochondrial fission 1 protein

1

1

High-throughput

0.479

High

166968

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.458

High

226155

STX6
Syntaxin-6

1

0

High-throughput

0.458

High

278919

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.458

High

1204884

MKS3
Meckelin

1

0

High-throughput

0.458

High

1365042

SNX27
Sorting nexin-27

1

0

High-throughput

0.458

High

1365061

ANLN
Anillin

1

0

High-throughput

0.458

High

1365071

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1365073

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

1365087

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

0

High-throughput

0.458

High

613419

VINC
Vinculin

1

4

High-throughput

0.445

High

1243641

S27A1
Long-chain fatty acid transport protein 1

1

1

High-throughput

0.445

High

188953

TMPS2
Transmembrane protease serine 2

1

5

High-throughput

0.437

High

189751

STX7
Syntaxin-7

1

2

High-throughput

0.437

High

302917

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

3

High-throughput

0.437

High

341116

DIRA3
GTP-binding protein Di-Ras3

1

4

High-throughput

0.437

High

439807

INSR
Insulin receptor

1

6

High-throughput

0.437

High

465594

IGF1R
Insulin-like growth factor 1 receptor

1

5

High-throughput

0.437

High

562277

LAMP2
Lysosome-associated membrane glycoprotein 2

1

6

High-throughput

0.437

High

589293

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

630598

RAB3B
Ras-related protein Rab-3B

1

3

High-throughput

0.437

High

630914

RAB4A
Ras-related protein Rab-4A

1

4

High-throughput

0.437

High

696081

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

768778

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

820705

CEAM6
Cell adhesion molecule CEACAM6

1

2

High-throughput

0.437

High

900962

RAB5C
Ras-related protein Rab-5C

1

4

High-throughput

0.437

High

945058

RAB25
Ras-related protein Rab-25

1

2

High-throughput

0.437

High

1004149

CXAR
Coxsackievirus and adenovirus receptor

1

2

High-throughput

0.437

High

1147651

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

2

High-throughput

0.437

High

1148867

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

2

High-throughput

0.437

High

1238759

TECT3
Tectonic-3

1

2

High-throughput

0.437

High

1254869

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.437

High

1278049

MAVS
Mitochondrial antiviral-signaling protein

1

5

High-throughput

0.437

High

1286850

TM11B
Transmembrane protease serine 11B

1

4

High-throughput

0.437

High

1294224

GOLI
E3 ubiquitin-protein ligase RNF130

1

16

High-throughput

0.437

High

1312204

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.437

High

1322924

CXD3
Gap junction delta-3 protein

1

5

High-throughput

0.437

High

1326994

DJC22
DnaJ homolog subfamily C member 22

1

2

High-throughput

0.437

High

1331229

ARL10
ADP-ribosylation factor-like protein 10

1

6

High-throughput

0.437

High

1360905

CLC4D
C-type lectin domain family 4 member D

1

2

High-throughput

0.437

High

1365037

S2546
Mitochondrial outer membrane protein SLC25A46

1

1

High-throughput

0.437

High

1365040

TECT2
Tectonic-2

1

2

High-throughput

0.437

High

1365046

RMD3
Regulator of microtubule dynamics protein 3

1

1

High-throughput

0.437

High

1365063

ST7
Suppressor of tumorigenicity 7 protein

1

2

High-throughput

0.437

High

1365064

TMPS4
Transmembrane protease serine 4

1

5

High-throughput

0.437

High

1365065

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

1

High-throughput

0.437

High

1365067

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

2

High-throughput

0.437

High

1365068

OCAD1
OCIA domain-containing protein 1

1

1

High-throughput

0.437

High

1365072

MTCH1
Mitochondrial carrier homolog 1

1

10

High-throughput

0.437

High

1365081

CLC4E
C-type lectin domain family 4 member E

1

2

High-throughput

0.437

High

1365082

ALK
ALK tyrosine kinase receptor

1

8

High-throughput

0.437

High

1365084

LAMP3
Lysosome-associated membrane glycoprotein 3

1

6

High-throughput

0.437

High

1365088

MTCH2
Mitochondrial carrier homolog 2

1

8

High-throughput

0.437

High

1365050

S12A9
Solute carrier family 12 member 9

1

5

High-throughput

0.407

High

992418

GBG1
Guanine nucleotide-binding protein G(T) subunit gamma-T1

2

0

High-throughput

0.316

High

1129255

LAGE3
EKC/KEOPS complex subunit LAGE3

1

0

High-throughput

0.279

Low

1365039

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

0

High-throughput

0.279

Low

281628

MTX2
Metaxin-2

1

0

High-throughput

0.249

Low

600349

ZNF24
Zinc finger protein 24

1

0

High-throughput

0.249

Low

1163386

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.249

Low

1211180

ODR4
Protein odr-4 homolog

1

0

High-throughput

0.249

Low

1288487

LBN
Limbin

1

0

High-throughput

0.249

Low

1293096

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1312565

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.249

Low

1335170

NOA1
Nitric oxide-associated protein 1

1

0

High-throughput

0.249

Low

1365059

SFXN1
Sideroflexin-1

1

0

High-throughput

0.249

Low

1365078

LTOR3
Ragulator complex protein LAMTOR3

1

0

High-throughput

0.249

Low

517253

AMY1B
Alpha-amylase 1B

1

0

High-throughput

0.232

Low

653473

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025