HitPredict

Interactor 1: CNG (Q03611)
Cyclic nucleotide-gated cation channel (Abnormal chemotaxis protein 4)
Gene: tax-4

Interactor 2: CNG (Q03611)
Cyclic nucleotide-gated cation channel (Abnormal chemotaxis protein 4)
Gene: tax-4

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.803

The method score is based on:

Property Details
Experiments 28279024, 28099415, 32483338
Identification Methods protein complementation assay, 3D electron microscopy, electron microscopy 3D single particle reconstruction
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CLZ~CLZ, cNMP_binding~cNMP_binding, Ion_trans~cNMP_binding, Ion_trans~Ion_trans
Common GO terms GO:0003031 - detection of carbon dioxide
GO:0005222 - intracellularly cAMP-activated cation channel activity
GO:0005223 - intracellularly cGMP-activated cation channel activity
GO:0005249 - voltage-gated potassium channel activity
GO:0005886 - plasma membrane
and 29 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 733
Ce

1 733
+ Ce
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Bt
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Ce

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Last updated: 15 Jul 2024