HitPredict

Interactor 1: HMO1 (Q03973)
High mobility group protein 1 (High spontaneous mutagenesis protein 2)
Gene: HMO1

Interactor 2: SMT3 (Q12306)
Ubiquitin-like protein SMT3
Gene: SMT3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.648

Property	Details
Experiments	18719252, 15590687, 23403034
Identification Methods	two hybrid, affinity chromatography technology, protein complementation assay
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 246 Sc			1 101
+	Hs
		902654 PB1_HUMAN (23-216): 9.66e-31: 122: 15.98		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		902545 SSRP1_HUMAN (21-234): 3.26e-28: 114: 18.34		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Sc
		705915 IXR1_YEAST (86-196): 1.72e-22: 97.7: 22.52		SMT3_YEAST (1-101): 1.79e-40: 130: 100.00
+	Hs
		727841 SOX6_HUMAN (38-186): 1.21e-25: 107: 13.91		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		928079 SSRP1_HUMAN (21-234): 3.26e-28: 114: 18.34		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44
+	Hs
		817866 SOX2_HUMAN (79-194): 4.37e-25: 102: 17.24		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		102151 SOX5_HUMAN (20-186): 8.26e-25: 104: 15.61		SUMO5_HUMAN (1-98): 4.98e-35: 117: 43.88
+	Hs
		817899 SOX2_HUMAN (79-194): 4.37e-25: 102: 17.24		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44
+	Hs
		617272 SP100_HUMAN (83-194): 1.55e-14: 74.6: 20.54		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		102150 SP100_HUMAN (83-194): 1.55e-14: 74.6: 20.54		SUMO5_HUMAN (1-98): 4.98e-35: 117: 43.88
+	Hs
		617270 SP100_HUMAN (83-194): 1.55e-14: 74.6: 20.54		SUMO3_HUMAN (9-98): 2.24e-34: 115: 43.96
+	Hs
		617277 SP100_HUMAN (83-194): 1.55e-14: 74.6: 20.54		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44
+	Dm
		332522 HMGD_DROME (104-179): 8.05e-09: 54.1: 19.74		O97102_DROME (13-99): 2.66e-35: 117: 43.18