HitPredict - High confidence protein-protein interactions

Interactor 1: ARI5A (Q03989)
AT-rich interactive domain-containing protein 5A (ARID domain-containing protein 5A) (Modulator recognition factor 1) (MRF-1)
Gene: ARID5A

Interactor 2: ARI5A (Q03989)
AT-rich interactive domain-containing protein 5A (ARID domain-containing protein 5A) (Modulator recognition factor 1) (MRF-1)
Gene: ARID5A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ARID~ARID
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000976 - transcription cis-regulatory region binding GO:0002062 - chondrocyte differentiation GO:0003677 - DNA binding GO:0003682 - chromatin binding and 25 others more... GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex GO:0005730 - nucleolus GO:0006357 - regulation of transcription by RNA polymerase II GO:0008134 - transcription factor binding GO:0030331 - nuclear estrogen receptor binding GO:0032729 - positive regulation of type II interferon production GO:0032740 - positive regulation of interleukin-17 production GO:0032755 - positive regulation of interleukin-6 production GO:0032760 - positive regulation of tumor necrosis factor production GO:0035613 - RNA stem-loop binding GO:0043565 - sequence-specific DNA binding GO:0045087 - innate immune response GO:0045892 - negative regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046965 - nuclear retinoid X receptor binding GO:0046966 - nuclear thyroid hormone receptor binding GO:0050681 - nuclear androgen receptor binding GO:0071222 - cellular response to lipopolysaccharide GO:0071391 - cellular response to estrogen stimulus GO:1901985 - positive regulation of protein acetylation GO:2000318 - positive regulation of T-helper 17 type immune response GO:2000556 - positive regulation of T-helper 1 cell cytokine production
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1	594
Hs

1	594

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Last updated: 15 Jul 2024