HitPredict - High confidence protein-protein interactions

Interactor 1: UBXN1 (Q04323)
UBX domain-containing protein 1 (SAPK substrate protein 1) (UBA/UBX 33.3 kDa protein)
Gene: UBXN1

Interactor 2: UBXN1 (Q04323)
UBX domain-containing protein 1 (SAPK substrate protein 1) (UBA/UBX 33.3 kDa protein)
Gene: UBXN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UBA~UBA, UBX~UBX
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005783 - endoplasmic reticulum GO:0005829 - cytosol and 14 others more... GO:0031397 - negative regulation of protein ubiquitination GO:0031593 - polyubiquitin modification-dependent protein binding GO:0031625 - ubiquitin protein ligase binding GO:0032435 - negative regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0034098 - VCP-NPL4-UFD1 AAA ATPase complex GO:0036435 - K48-linked polyubiquitin modification-dependent protein binding GO:0043130 - ubiquitin binding GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0051117 - ATPase binding GO:0071796 - K6-linked polyubiquitin modification-dependent protein binding GO:1903094 - negative regulation of protein K48-linked deubiquitination GO:1904293 - negative regulation of ERAD pathway GO:1904855 - proteasome regulatory particle binding GO:2000157 - negative regulation of ubiquitin-specific protease activity
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1	297
Hs

1	297

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Last updated: 15 Jul 2024