HitPredict

Interactor 1: UBXN1 (Q04323)
UBX domain-containing protein 1 (SAPK substrate protein 1) (UBA/UBX 33.3 kDa protein)
Gene: UBXN1

Interactor 2: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36688959
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0031625 - ubiquitin protein ligase binding GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 297 Hs			1 759
+	Hs
		299370 UBXN7_HUMAN (45-294): 2.33e-43: 156: 17.13		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		299371 UBXN7_HUMAN (45-294): 2.33e-43: 156: 17.13		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		979295 UBXN1_HUMAN (1-297): 5.45e-68: 215: 100.00		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		299369 UBXN7_HUMAN (45-294): 2.33e-43: 156: 17.13		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1042842 FAF1_HUMAN (71-294): 1.76e-41: 153: 22.12		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		979293 UBXN1_HUMAN (1-297): 5.45e-68: 215: 100.00		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		979294 UBXN1_HUMAN (1-297): 5.45e-68: 215: 100.00		CUL2_HUMAN (51-759): 0: 710: 27.00
+	Hs
		299367 UBXN7_HUMAN (45-294): 2.33e-43: 156: 17.13		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		1041280 FAF1_HUMAN (71-294): 1.76e-41: 153: 22.12		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		1042130 UBS3B_HUMAN (5-73): 4.15e-16: 80.4: 46.38		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		299368 UBXN7_HUMAN (45-294): 2.33e-43: 156: 17.13		CUL2_HUMAN (51-759): 0: 710: 27.00
+	Hs
		1041502 FAF1_HUMAN (71-294): 1.76e-41: 153: 22.12		CUL2_HUMAN (51-759): 0: 710: 27.00