HitPredict

Interactor 1: TLE1 (Q04724)
Transducin-like enhancer protein 1 (E(Sp1) homolog) (Enhancer of split groucho-like protein 1) (ESG1)
Gene: TLE1

Interactor 2: HESX1 (Q9UBX0)
Homeobox expressed in ES cells 1 (Homeobox protein ANF) (hAnf)
Gene: HESX1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	11731482
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 770 Hs			1 185
+	Hs
		620142 TLE1_HUMAN (1-770): 0: 594: 100.00		PAX7_HUMAN (77-172): 2.13e-37: 136: 35.42
+	Hs
		980644 TLE1_HUMAN (1-770): 0: 594: 100.00		BARH1_HUMAN (9-185): 2.7e-32: 119: 22.60
+	Hs
		882121 TLE1_HUMAN (1-770): 0: 594: 100.00		GSC_HUMAN (3-178): 5.26e-31: 114: 25.51
+	Hs
		980659 TLE1_HUMAN (1-770): 0: 594: 100.00		VSX1_HUMAN (36-169): 6.1e-30: 114: 29.10
+	Hs
		620144 TLE4_HUMAN (1-770): 0: 562: 86.27		PAX7_HUMAN (77-172): 2.13e-37: 136: 35.42
+	Mm
		623700 TLE4_MOUSE (1-770): 0: 563: 86.27		PAX3_MOUSE (32-173): 4.18e-35: 129: 28.17
+	Hs
		882123 TLE4_HUMAN (1-770): 0: 562: 86.27		GSC_HUMAN (3-178): 5.26e-31: 114: 25.51
+	Hs
		980956 TLE4_HUMAN (1-770): 0: 562: 86.27		VSX1_HUMAN (36-169): 6.1e-30: 114: 29.10
+	Hs
		641377 TLE1_HUMAN (1-770): 0: 594: 100.00		PAX6_HUMAN (84-168): 8.15e-14: 70.5: 48.24
+	Hs
		620143 TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42		PAX7_HUMAN (77-172): 2.13e-37: 136: 35.42
+	Hs
		882122 TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42		GSC_HUMAN (3-178): 5.26e-31: 114: 25.51
+	Hs
		980893 TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42		VSX1_HUMAN (36-169): 6.1e-30: 114: 29.10
+	Hs
		641379 TLE4_HUMAN (1-770): 0: 562: 86.27		PAX6_HUMAN (84-168): 8.15e-14: 70.5: 48.24
+	Hs
		641378 TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42		PAX6_HUMAN (84-168): 8.15e-14: 70.5: 48.24
+	Hs
		980714 TLE2_HUMAN (1-770): 2e-150: 458: 64.85		BARH1_HUMAN (9-185): 2.7e-32: 119: 22.60
+	Dm
		558366 GROU_DROME (1-770): 7.74e-141: 433: 59.79		UBX_DROME (39-172): 3.14e-30: 115: 25.37
+	Dm
		558365 GROU_DROME (1-770): 7.74e-141: 433: 59.79		GSC_DROME (107-171): 1.3e-13: 69.7: 49.23
+	Dm
		185801 GROU_DROME (1-770): 7.74e-141: 433: 59.79		PAX6_DROME (84-168): 2.55e-12: 66.2: 45.88
+	Hs
		620146 TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50		PAX7_HUMAN (77-172): 2.13e-37: 136: 35.42
+	Hs
		641385 TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50		PAX6_HUMAN (84-168): 8.15e-14: 70.5: 48.24