HitPredict

Interactor 1: TLE3 (Q04726)
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Gene: TLE3

Interactor 2: KLF5 (Q13887)
Krueppel-like factor 5 (Basic transcription element-binding protein 2) (BTE-binding protein 2) (Colon krueppel-like factor) (GC-box-binding protein 2) (Intestinal-enriched krueppel-like factor) (Transcription factor BTEB2)
Gene: KLF5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35140242, 37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 772 Hs			1 457
+	Hs
		980601 TLE1_HUMAN (1-772): 0: 538: 77.42		KLF5_HUMAN (1-457): 3.24e-124: 370: 100.00
+	Hs
		884134 TLE3_HUMAN (1-772): 0: 583: 100.00		KLF3_HUMAN (308-455): 2.48e-37: 141: 59.33
+	Hs
		980959 TLE4_HUMAN (1-772): 9.37e-179: 533: 80.65		KLF12_HUMAN (353-455): 4.09e-44: 160: 76.92
+	Hs
		993418 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		KLF5_HUMAN (1-457): 3.24e-124: 370: 100.00
+	Hs
		884133 TLE1_HUMAN (1-772): 0: 538: 77.42		KLF3_HUMAN (308-455): 2.48e-37: 141: 59.33
+	Hs
		204165 TLE1_HUMAN (1-772): 0: 538: 77.42		KLF4_HUMAN (361-455): 3e-34: 135: 75.79
+	Hs
		993504 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		ZN383_HUMAN (78-457): 7.39e-78: 251: 16.28
+	Hs
		316865 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		KLF8_HUMAN (366-455): 4.48e-40: 149: 78.89
+	Hs
		993414 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		KLF1_HUMAN (356-455): 3.87e-38: 144: 73.00
+	Hs
		884139 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		KLF3_HUMAN (308-455): 2.48e-37: 141: 59.33
+	Hs
		204169 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		KLF4_HUMAN (361-455): 3e-34: 135: 75.79
+	Ce
		137695 UNC37_CAEEL (18-686): 7.48e-82: 275: 17.09		KLF1_CAEEL (349-455): 2.77e-40: 152: 64.49
+	Hs
		158029 TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07		KLF11_HUMAN (366-455): 1.77e-29: 122: 65.56
+	Hs
		903644 WDR5_HUMAN (284-560): 2.42e-32: 130: 9.12		KLF12_HUMAN (353-455): 4.09e-44: 160: 76.92
+	Hs
		884122 WDR5_HUMAN (284-560): 2.42e-32: 130: 9.12		KLF3_HUMAN (308-455): 2.48e-37: 141: 59.33
+	Hs
		1315361 GBB4_HUMAN (441-646): 3.79e-39: 150: 20.00		KLF16_HUMAN (373-455): 1.97e-30: 120: 63.86
+	Hs
		903489 WDR5_HUMAN (284-560): 2.42e-32: 130: 9.12		KLF16_HUMAN (373-455): 1.97e-30: 120: 63.86