HitPredict

Interactor 1: REL (Q04864)
Proto-oncogene c-Rel
Gene: REL

Interactor 2: HDAC7 (Q8WUI4)
Histone deacetylase 7 (HD7) (EC 3.5.1.98) (Histone deacetylase 7A) (HD7a) (Protein deacetylase HDAC7) (EC 3.5.1.-)
Gene: HDAC7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 619 Hs			1 952
+	Hs
		587484 NFKB1_HUMAN (1-375): 2e-145: 447: 37.47		HDAC4_HUMAN (20-939): 0: 958: 48.44
+	Hs
		587753 NFKB1_HUMAN (1-375): 2e-145: 447: 37.47		HDAC5_HUMAN (20-950): 0: 850: 41.21
+	Rn
		1118084 Q7TQN4_RAT (2-576): 2.12e-167: 490: 38.48		HDAC1_RAT (510-916): 5.08e-171: 508: 21.91
+	Mm
		140259 TF65_MOUSE (2-576): 1.99e-167: 490: 38.89		HDAC1_MOUSE (510-916): 5.08e-171: 508: 21.91
+	Mm
		936384 TF65_MOUSE (2-576): 1.99e-167: 490: 38.89		HDAC2_MOUSE (513-948): 1.36e-166: 497: 20.71
+	Mm
		140230 NFKB1_MOUSE (1-414): 1.82e-152: 465: 33.56		HDAC1_MOUSE (510-916): 5.08e-171: 508: 21.91
+	Hs
		978743 TF65_HUMAN (2-576): 4.74e-158: 466: 37.89		HDAC1_HUMAN (510-916): 1.27e-170: 507: 21.91
+	Mm
		292411 TF65_MOUSE (2-576): 1.99e-167: 490: 38.89		HDAC3_MOUSE (518-951): 2.02e-161: 481: 20.00
+	Hs
		978828 TF65_HUMAN (2-576): 4.74e-158: 466: 37.89		HDAC2_HUMAN (513-948): 3.43e-167: 499: 20.71
+	Hs
		587561 NFKB1_HUMAN (1-375): 2e-145: 447: 37.47		HDAC1_HUMAN (510-916): 1.27e-170: 507: 21.91
+	Hs
		177267 TF65_HUMAN (2-576): 4.74e-158: 466: 37.89		HDAC3_HUMAN (518-951): 2.59e-161: 481: 20.00
+	Mm
		292405 NFKB1_MOUSE (1-414): 1.82e-152: 465: 33.56		HDAC3_MOUSE (518-951): 2.02e-161: 481: 20.00
+	Hs
		587651 NFKB1_HUMAN (1-375): 2e-145: 447: 37.47		HDAC2_HUMAN (513-948): 3.43e-167: 499: 20.71
+	Mm
		140260 RELB_MOUSE (2-479): 6.01e-144: 430: 35.25		HDAC1_MOUSE (510-916): 5.08e-171: 508: 21.91
+	Hs
		177192 NFKB1_HUMAN (1-375): 2e-145: 447: 37.47		HDAC3_HUMAN (518-951): 2.59e-161: 481: 20.00
+	Mm
		292412 RELB_MOUSE (2-479): 6.01e-144: 430: 35.25		HDAC3_MOUSE (518-951): 2.02e-161: 481: 20.00
+	Mm
		978993 TF65_MOUSE (2-576): 1.99e-167: 490: 38.89		HDAC6_MOUSE (451-900): 4.8e-121: 398: 32.54
+	Mm
		638477 NFKB1_MOUSE (1-414): 1.82e-152: 465: 33.56		HDAC6_MOUSE (451-900): 4.8e-121: 398: 32.54
+	Hs
		978923 TF65_HUMAN (2-576): 4.74e-158: 466: 37.89		HDAC6_HUMAN (443-951): 2.96e-115: 383: 30.33
+	Hs
		964534 RELB_HUMAN (2-479): 1.52e-143: 430: 35.04		HDAC6_HUMAN (443-951): 2.96e-115: 383: 30.33